The 2016 Soul Train Music Awards was held at the Orleans Arena in Las Vegas, Nevada, on November 6, 2016. It was later aired on Centric and BET on November 27, 2016. The ceremony, hosted by Erykah Badu for the second year in a row, honored artists in 12 different categories. Drake was the most nominated artist with twelve, followed by Beyoncé (10) and Rihanna (8). During the ceremony american singer and songwriter Brandy was honored with the Lady of Soul Award for her contributions to the music industry. Teddy Riley was recognized by the Legend Award for his successful songwriting and music producing works.

Winners are listed first and highlighted in bold.