The 2018 FIM Moto2 World Championship was a part of the 70th F.I.M. Road Racing World Championship season. Franco Morbidelli was the reigning series champion, but he did not defend his title as he moved to the MotoGP class.

2018 was the final season that the Honda CBR600RR inline-4 engine package — which debuted in the 2010 Moto2 season — was used in competition; as a brand new engine package (765cc inline-3) supplied by Triumph Motorcycles was introduced for the 2019 season.

After finishing 3rd at Sepang, Italian rider Francesco Bagnaia became the 2018 Moto2 World Champion. Miguel Oliveira finished second in the championship and his teammate Brad Binder finished third.

All the bikes used series-specified Dunlop tyres and Honda 600cc 4-cylinder engine.

The following Grands Prix were scheduled to take place in 2018:

Points were awarded to the top fifteen finishers. A rider had to finish the race to earn points.

Each constructor received the same number of points as their best placed rider in each race.

The teams' standings were based on results obtained by regular and substitute riders; wild-card entries were ineligible.