An election was held on November 8, 2022, to elect all 110 members to Michigan's House of Representatives. The election coincided with elections for other offices, including governor, State Senate and U.S. House of Representatives. Democrats won a majority of 56 out of 110 seats, winning control of the chamber for the first time since 2008.

This was the first election to take place after redistricting based on the 2020 United States census. Following the approval of a voter-initiated constitutional amendment in 2018, the responsibility for legislative and congressional reapportionment was transferred from the state legislature to a 13-member citizens commission. Many blamed the maps drawn by Republicans after the 2010 census for enabling the party to maintain control of the legislature throughout the decade despite losing the statewide popular vote multiple times. In 2020, the Republican Party had narrowly retained their majority of the chamber.

Despite expectations that Republicans would maintain control, Democrats gained three seats, giving them a majority of 56 out of 110 seats and winning control of the chamber for the first time since 2008. Simultaneously with Democrats gains in the state senate, winning control of that chamber the first time since 1984, and Governor Gretchen Whitmer winning re-election, Democrats won a trifecta in the state for the first time in 40 years. Democrats benefited from a more favorable map than they had in the previous decade, as well as the down-ballot effects of Whitmer's victory and the passage of a referendum on abortion rights.

Seats where the margin of victory was under 10%:

All results below are from the certified election results posted by the secretary of state.