The 2022 Sofia Twenty20 tournament was a Twenty20 International (T20I) cricket tournament which was held in Sofia, Bulgaria, in June 2022. This was the second edition of the Sofia Twenty20; the 2021 tournament was contested by four nations, but the 2022 edition took the form of a four-match bilateral series between Bulgaria and Serbia. The series was played at the National Sports Academy in Sofia.^{[dead link]} The series provided both teams with preparation for the 2022–23 ICC Men's T20 World Cup Europe Qualifier subregional tournaments.