The 2022 Wrexham County Borough Council election took place on 5 May 2022 to elect 56 members to Wrexham County Borough Council, the principal council of Wrexham County Borough, Wales. On the same day, elections were held to the other 21 local authorities, and community councils in Wales as part of the 2022 Welsh local elections. The previous Wrexham County Borough all-council election took place in May 2017 and future elections will take place every five years, with the next scheduled for 2027.

On 5 May 2022, the election was held in forty-one of the forty-nine wards for 2022 in Wrexham County Borough. The remaining eight had no opposition nominated by 5 April 2022, and the councillors for these wards were re-elected unopposed, with their wards not holding the election. The councillors unopposed were six independents and two conservative councillors.

Independent politicians (including "non-specified" and the "Wrexham Independents") formed the largest group in the council with twenty-three councillors, down from 2017's twenty-six, and were six short of the twenty-nine needed for a majority. The second largest group were Labour with fourteen councillors elected, up from 2017's twelve councillors. The Conservatives had the same amount councillors as in 2017 with nine. Plaid Cymru increased their number of councillors to match the Conservatives also at nine, up from their three councillors in 2017. The Liberal Democrats had their share of councillors split to one councillor, down from two in 2017.

Following the results, the council was again under no overall control. Talks between independent politicians and Labour occurred over the weekend. On 10 May 2022, the two formerly separately organised groups of independents in the council, the independents and the "Wrexham Independents" group, merged into one "mega" 21-member "Independent Group". The Independent Group was initially in talks with Welsh Labour councillors but talks collapsed over mandatory councillor anti-discrimination training. On 11 May 2022, the Independent Group formed another coalition with the Welsh Conservatives for another five-year term with a total of thirty members, a two-member majority.

Council elections in Wales were originally scheduled for May 2021 but were delayed to avoid a conflict with the 2021 Senedd election. The frequency of the elections was also increased from four years to five years to avoid future clashes, meaning (after 2022) the next council election is expected in 2027. The number of councillors is to be increased from fifty-two to fifty-six at the 2022 election, with several ward changes to ensure better electoral parity. There would be forty-nine wards up for election, up from forty-seven in the 2017 election following a recent local boundary review.

An Independent–Welsh Conservatives coalition group was formed following the 2017 local election and were in control of the council since 2017 up to the election.

In the 2019 United Kingdom general election, Conservative candidates won the constituencies of Wrexham and Clwyd South for the first time in their existence. The constituencies were generally considered to be Labour heartlands part of its "red wall", and were won by Labour in the June 2017 election. Sarah Atherton was elected for the Conservatives to represent the Wrexham constituency with 15,199 votes, and Simon Baynes for Clwyd South with 16,222 votes. Atherton is the first Female MP to be elected to the Wrexham seat since its creation in 1918, and the first female Conservative MP elected to Westminster representing a Welsh constituency.

On 31 January 2020, the UK left the EU, with the county borough in the 2016 referendum, voting 59% in favour of Leave.