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AL-37350A
AL-37350A, also known as 4,5-dihydropyrano-α-methyltryptamine (4,5-DHP-AMT), is a serotonin receptor agonist and tricyclic tryptamine derivative related to the psychedelic tryptamine 5-MeO-AMT. It acts as a potent and selective agonist for the serotonin receptor 5-HT2A, with a Ki of 2.0 nM, and moderate selectivity over the related 5-HT2B and 5-HT2C receptors. The drug has been shown to have ocular hypotensive activity in animal models, suggesting it may be useful for the treatment of glaucoma. AL-37350A was first described in the scientific literature by Jesse May and colleagues in 2003.
AL-37350A
AL-37350A, also known as 4,5-dihydropyrano-α-methyltryptamine (4,5-DHP-AMT), is a serotonin receptor agonist and tricyclic tryptamine derivative related to the psychedelic tryptamine 5-MeO-AMT. It acts as a potent and selective agonist for the serotonin receptor 5-HT2A, with a Ki of 2.0 nM, and moderate selectivity over the related 5-HT2B and 5-HT2C receptors. The drug has been shown to have ocular hypotensive activity in animal models, suggesting it may be useful for the treatment of glaucoma. AL-37350A was first described in the scientific literature by Jesse May and colleagues in 2003.