Al-Razi recognized the importance of cleanliness and sanitation in preventing the spread of diseases. He stressed the need for maintaining clean living environments, disposing of waste properly, and practicing good personal hygiene. He understood the connection between sanitation and disease transmission.

Al-Razi emphasized the importance of clean air and water for maintaining health. He recommended locating cities and homes in areas with fresh air and clean water sources. He advocated for measures to prevent the pollution of water sources and to ensure the quality of drinking water.

Al-Razi understood the nature of infectious diseases and advocated for measures to control their spread. He recommended isolating infected individuals, disinfecting contaminated objects, and implementing quarantine measures to prevent epidemics. His treatise on smallpox and measles directly contributed to understanding and managing infectious diseases.