Al-Razi demonstrated an early interest in alchemy and spent considerable time studying alchemical theories and practices. This interest likely contributed to his understanding of chemical substances and their properties.

Al-Razi adopted a more experimental and systematic approach to alchemy than many of his predecessors. He emphasized the importance of conducting experiments and carefully observing the results.

Al-Razi made contributions to the classification of chemical substances, categorizing them into different groups based on their properties and origins. His classification scheme reflected his understanding of chemical compounds and their interactions. He categorized substances into animals, vegetables, and minerals.

Al-Razi is credited with the discovery and description of several chemical compounds, including sulfuric acid, alcohol and other important substances that were used in medicine and alchemy. These discoveries were the result of his experimental work in chemistry.