Academia Sinica (AS; Latin: Academia Sinica; Chinese: 中央研究院) is the national academy of the Republic of China (Taiwan). It is headquartered in Nangang, Taipei.

Founded in Nanjing, the academy supports research activities in mathematics, physical sciences, life sciences, humanities and social sciences. As an educational institute, it provides PhD training and scholarship through its English-language Taiwan International Graduate Program in biology, agriculture, chemistry, physics, informatics, and earth and environmental sciences.

The current president since 2016 is James C. Liao, an expert in metabolic engineering, systems biology and synthetic biology.

Academia Sinica, which means "Chinese Academy", was founded in 1928 in Nanjing, then capital of the Republic of China, with its first meeting held in Shanghai. By December 1948, all fourteen institutes of the Academia Sinica had agreed to move from Nanjing to Taiwan alongside other institutions of the government of the Republic of China as a result of the Chinese Civil War. In the end, only the Academia Sinica's Institute of History and Philology was relocated to Taiwan, because the head of the Institute of Mathematics, Jiang Lifu, resigned his position in June 1949, and never traveled to Taiwan.

Of the 81 inaugural research fellows appointed by the Academia Sinica prior to its move, nine crossed the Taiwan Strait. The institution was low on monetary funds, and reopened with the Institute of History and Philology in December 1954. In the same year, its main campus was constructed in Jiuzhuang [zh], Nangang, Taipei. Due to the importance of agriculture to the economy of Taiwan, efforts were made to revive the Institute of Botany. The second convocation of the Academia Sinica was held in 1957. At the same time, the mainland part of Academia Sinica remained functioning under Communist rule and was renamed as the Chinese Academy of Sciences in the 1980s.

In the 2000s, many of the current institutes and research centers were established, partially through reorganization of old ones. Academia Sinica's first PhD program, the Taiwan International Graduate Program, was inaugurated in 2006.^{[citation needed]}

The president of Academia Sinica is appointed by the president of the Republic of China (Taiwan) from three candidates recommended by the Council Meeting. The president of Academia Sinica must be an academician. After the appointment, the president serves a five-year term and can serve up to two consecutive terms.

Academia Sinica's current president is James C. Liao, a biochemist, who replaced Chi-Huey Wong, a biological chemist and the Parsons Foundation Professor and Chair of the Department of Chemical and Biomolecular Engineering at the University of California, Los Angeles, as the 11th president on 21 June 2016.^{[citation needed]} The list of past presidents also includes Hu Shih, a philosopher and essayist, and a key contributor to Chinese liberalism and language reform in his advocacy for the use of vernacular Chinese, as well as an influential redology scholar and holder of the Jiaxu manuscript (Chinese: 甲戌本; pinyin: Jiǎxū běn) until his death. The fifth president, Yuan T. Lee, won the Nobel Prize in Chemistry for "contributions to the dynamics of chemical elementary processes".