Advise & Consent is a 1962 American political drama film based on the Pulitzer Prize-winning novel Advise and Consent by Allen Drury, published in 1959. It was adapted for the screen by Wendell Mayes and was directed by Otto Preminger. The film, set in Washington, D.C., follows the nomination process of a man who commits perjury in confirmation hearings for his nomination as Secretary of State.

The title derives from the United States Constitution's Article II, Sec. 2, cl. 2, which provides that the president of the United States "shall nominate, and by and with the Advice and Consent of the Senate, shall appoint Ambassadors, other public Ministers and Consuls, Judges of the Supreme Court, and all other Officers of the United States."

The ensemble cast features Henry Fonda, Charles Laughton (in his final film role), Don Murray, Walter Pidgeon, Peter Lawford, Gene Tierney, Franchot Tone, Lew Ayres, Burgess Meredith, Eddie Hodges, Paul Ford, George Grizzard, Inga Swenson, Betty White, Edward Andrews, and others.

The president nominates Robert A. Leffingwell as Secretary of State. The second-term president, who is ill, has chosen him in part because he does not believe that Vice President Harley Hudson, whom both he and others usually ignore, will successfully continue the administration's foreign policy should the president die.

Leffingwell's nomination is controversial within the Senate, which must use its advice and consent powers to approve or reject the appointment. The parties of both the president and the minority are divided. Senate Majority Leader Bob Munson, the senior senator from Michigan, loyally supports the nominee despite his doubts, as do the hard-working majority whip Stanley Danta of Connecticut and womanizer Lafe Smith of Rhode Island. Demagogic peace advocate Fred Van Ackerman of Wyoming is especially supportive, but Munson repeatedly advises him not to aggravate the situation. Although also of the majority party, the curmudgeonly president pro tempore Seabright "Seab" Cooley of South Carolina dislikes Leffingwell for both personal and professional reasons and leads the opposition.

The Senate Foreign Relations Committee appoints a subcommittee, chaired by majority member Brigham Anderson of Utah, to evaluate the nominee. The young and devoted family man is undecided on Leffingwell. Cooley dramatically introduces a surprise witness, Herbert Gelman, during the subcommittee's hearing. The minor Treasury Department clerk testifies that he was briefly affiliated with a communist cell with Leffingwell and two others at the University of Chicago. Leffingwell denies the charge and questions Gelman's credibility but later tells the president that he had committed perjury and that Gelman was telling the truth. He asks the president to withdraw his nomination, but the president refuses.

Cooley identifies another member of the cell, senior Treasury official Hardiman Fletcher. He forces Fletcher to confess to Anderson, who tells Munson. Despite personal lobbying by the president, the subcommittee chairman insists that the White House withdraw the nomination because of Leffingwell's perjury or he will subpoena Fletcher to testify. The president angrily refuses, but the majority leader admits that the White House will soon have to nominate another candidate. Anderson delays his committee's report on Leffingwell, but the president sends Fletcher out of the country, angering the senator.

Anderson's wife receives anonymous phone calls from a man warning that unless the subcommittee reports favorably on Leffingwell, information about what happened with "Ray" in Hawaii will be disclosed. A worried Anderson visits fellow army veteran Ray Schaff in New York. Schaff admits that he sold evidence of a past homosexual relationship between the two. Vice President Hudson and Anderson's friend Smith join others in attempting to counsel the troubled chairman, but unable to reconcile his duty and his secret, Anderson takes his own life.