The Afrīdī (Pashto: اپريدی Aprīdai, plur. اپريدي Aprīdī; Urdu: آفریدی) are a Pashtun tribe present mostly in tribal areas in Khyber Pakhtunkhwa, Pakistan.

The Afridis are most dominant in the Spin Ghar range west of Peshawar in Tribal areas of modern-day Khyber Pakhtunkhwa, covering most of the Khyber Pass and Maidan in Tirah which is their Native Tribal Territory. They are the closest to Orakzai in their language, culture and geographic areas.

Herodotus, in his Histories, mentions an Indian tribe named Aparytai (Ἀπαρύται) inhabiting the Achaemenid satrapy of Arachosia. Thomas Holdich and Olaf Caroe have linked them with the Afridi tribe:

The Sattagydae, Gandarii, Dadicae, and Aparytae (Ἀπαρύται) paid together a hundred and seventy talents; this was the seventh province

— Herodotus, The Histories, Book III, Chapter 91, Section 4

The origin of the Afridis is uncertain. Among the Afridi six Ḵaybar clans are generally distinguished: the Kūkī Ḵēl, Kambar Ḵēl, Kamar Ḵēl, Malek-dīn Ḵēl, Sepāh, and Zakkā Ḵēl (or Zəḵā Ḵēl), in the Khyber pass region. In addition, there are two "assimilated clans" not recognized by the first six, the Akā Ḵēl, settled south of the Bārā river in contact with the Ōrakzī, and the Ādam Ḵēl, occupying a mountainous region between Peshawar and Kohat. This complex clan structure,  perhaps reflects the diversity of the origins of the different ethnic groups forming this great tribe.

The Afridis and their allies Khalils were first mentioned in the memoirs of Mughal Emperor Babar as violent tribes in need of subduing. The Afridi tribes controlled the Khyber Pass, which has served as a corridor connecting the Indian subcontinent with Afghanistan and Central Asia. Its strategic value was not lost on the Mughals to whom the Afridis were implacably hostile.

Over the course of Mughal rule, Emperors Akbar and Jahangir both dispatched punitive expeditions to suppress the Afridis, with little success.