Akio Otsuka (大塚 明夫, Ōtsuka Akio; born November 24, 1959) is a Japanese actor, voice actor, and narrator from the Tokyo Metropolitan area. He is currently a freelancer, but had previously been attached to Mausu Promotion.

The warm, calm quality of his deep voice has landed him many roles in films, dubbing, animation, and video games. He is most known for the roles of second generation Jigen Daisuke in Lupin III, the titular protagonist in Black Jack, Solid Snake, Naked Snake, Solidus Snake, and Venom Snake in the Metal Gear series, Gamigami Devil in Popolocrois, Ryoma Hoshi in Danganronpa V3: Killing Harmony, Shunsui Kyouraku in Bleach, Lieutenant Garuru in Sgt. Frog, Gwendel von Voltaire in Kyo Kara Maoh!, Batou in Ghost in the Shell, Blackbeard in One Piece, Tadakatsu Honda in the Samurai Warriors and Warriors Orochi series, Sango and Jugo Yokomizo in Detective Conan, Bryan Hawk in Hajime no Ippo, Zen Shigaraki/All For One in My Hero Academia, Thorkell in Vinland Saga, Wamuu in JoJo's Bizarre Adventure, Anavel Gato in Mobile Suit Gundam 0083: Stardust Memory, and Xehanort in the Kingdom Hearts series. He is the son of Chikao Ohtsuka.

He is also the official dub voice for many Western actors, including Steven Seagal, Nicolas Cage, Antonio Banderas, Dolph Lundgren, Samuel L. Jackson, Denzel Washington, and Dennis Quaid.

Mausu Promotion announced on January 7, 2017 that Otsuka had married someone outside of the voice acting industry.

On March 31, 2026, Mausu Promotion announced that Otsuka had left the agency to become an independent voice actor.