Altered States

Altered States is a 1980 American science fiction horror film directed by Ken Russell, and adapted by playwright and screenwriter Paddy Chayefsky from his 1978 novel of the same name. The novel and the film are based in part on John C. Lilly's sensory deprivation research conducted in isolation tanks under the influence of psychoactive drugs like mescaline, ketamine, and LSD. The film features elements of both psychological horror and body horror.

Chayefsky withdrew from the project after disputes with Russell and took his name off the credits, substituting "Sidney Aaron", his actual first and middle names. The film stars William Hurt, Blair Brown, Bob Balaban, and Charles Haid. It marked the film debut of Hurt and Drew Barrymore (in a small role). The film score was composed by John Corigliano and conducted by Christopher Keene.

Warner Bros. gave the film a limited theatrical release in the United States on December 25, 1980, followed by a wide release in February 1981. The film garnered generally positive reviews from critics, and was nominated for Best Original Score and Best Sound at the 53rd Academy Awards.

In 1967, Edward Jessup is a Columbia University psychopathologist studying schizophrenia. He begins to think that "our other states of consciousness are as real as our waking states." He begins experimenting with sensory deprivation using a flotation tank, aided by two like-minded researchers, Arthur Rosenberg and Mason Parrish. At a faculty party, he meets fellow "whiz kid," and his future wife, Emily.

Over a decade later, Edward is a tenured professor at Harvard Medical School. He and Emily have two daughters, and are on the brink of divorce, when they reunite – for the first time in seven years – with the couple who had first introduced them. When Edward hears about the Hinchi tribe, whose members experience shared hallucinatory states, he decides to travel to Mexico in order to participate in their ceremony.

During the climb up into the Hinchi hill country (a plateau covered in spectacular mushroom-shaped ventifacts), Edward is told by his guide, Eduardo Echeverria, that the Hinchi use in their ceremonies a potion containing the sacred mushroom Amanita muscaria and the shrub sinicuiche, which they are collecting for next year's ceremonies. The tribe calls sinicuiche by a Hinchi name meaning "first/primordial flower" in recognition of the deep memory states which it can evoke. An indigenous elder ("the brujo") is seen with a root in his hand, which he asks Edward to hold, before cutting Edward's hand in order to add some drops of blood to the mixture he is preparing. Immediately after consuming the mixture, Edward experiences bizarre, intense hallucinations, including one of the petrifaction and subsequent erosion by blown sand of Emily and himself.

The following morning, Edward leaves the Hinchi plateau under a cloud, having killed, while in his intoxicated state, a large specimen of the Hinchi's sacred monitor lizard (which a petroglyph shown in the dream sequence shows that they believe to have given them the sacred mushroom in the mythic past). He returns to the U.S. with a sample of the Hinchi potion for analysis by his colleagues and further self-experimentation, and continues taking it in order to take his exploration of altered states of consciousness to a new and higher level.

When toxic concentrations of the substance make increased dosage dangerous, Edward returns to sensory deprivation, believing it will enhance the effects of the substance at his current dose. Repairing a disused tank in a medical school, Edward uses it to experience a series of increasingly drastic visions, including one of early Hominidae. Monitored by his colleagues, Edward insists that his visions have "externalized". Emerging from the tank, his mouth bloody, frantically writing notes because he is unable to speak, Edward insists on being X-rayed before he "reconstitutes." A radiologist inspecting the X-rays says they belong to a gorilla.