Americans in Ireland comprise Irish citizens and residents who have full or partial American descent or ancestral background. These individuals often use the term 'American-Irish', in order to differentiate from the Irish-American cultural group.

Those with American-Irish dual citizenship represent 16.8% of all Irish people with dual nationality. As of 2016, there are 10,519 Americans in Ireland without any Irish citizenship.

Voter registration drives occurred in the run-up to the 2020 American Presidential Election. Democrats Abroad maintains a notable political base in the country. Cultural events, such as the Fourth of July and Thanksgiving are celebrated by the resident American population, as well as other affiliated groups. Several towns with large American populations host fireworks displays, while the American Chamber of Commerce hosts an annual Thanksgiving dinner, which is attended by the Taoiseach.