The ancient Tamil music is the historical predecessor of the Carnatic music during the Sangam period spanning from 500 BCE to 200 CE.

Many poems of the classical Sangam literature were set to music. There are various references to this ancient musical tradition found in the ancient Sangam books such as Ettuthokai and Pattupattu. The early narrative poem Cilappatikaram, belonging to the post-Sangam period (5th or 6th century) also mentions various forms of music practiced by the Tamil people.

Music was an integral part of the compositions of the Tamil Saiva saints such as Appar, Siva Prakasar, Thirugnana Sambanthar and Manikkavasagar during the Hindu revival period between the 6th and the 10th century.

The Sangam age grammatical work Tolkappiyam mentions the various music pertaining to the five landscapes (thinai) of the Sangam literature. The five landscapes are associated with a particular mood of the poem and to give colour to these moods, each had a musical mood (pann), a melodic instrument (yaazh) and a percussion instrument (parai). For example, the neithal thinai, which dealt with the incidents around the seashore and the theme of elopement, had the musical mood of sevvazhi, Vilari yaazh as the musical instrument and the navayapambai for the percussion. Tolkappiyam also mentions the musical form known as Paattu Vannam and various types of songs like Asiriapattu, Neduven pattu, Adivarai, Seer, Ahaval Osai and Vellosai, which are classified on the basis of the musical quality, metrical structure etc. Most of the Sangam age poetry used one or more of these meters in their compositions. Poems of the Ettuthohai anthology, such as the Natrinai, Paripaatal and Kaliththokai are extensively musical in nature and use various panns to create the mood.

Poems of the Sangam literature contain numerous mentions of the various musical instruments such as the Seerkazhi, a stringed instrument of the Veena type and various percussion instruments such as murasu or muzham. Pattupaatu contains a description of the yazh, a stringed instrument. There were two types of yaazh, Periyaazh or the 'large yaazh' contained 21 strings, whereas its more compact companion Siriyaazh had only seven strings. Two other types of yaazhs, Makarayaazh with 19 strings and Sakottuyaazh with seven strings are also mentioned in Pattuppattu. However, we have no further information on their actual appearance, mode of playing and the kind of melody generated by these instruments.

The flute was the most popular wind instrument during the Sangam period. Perumpanarruppatai, one of the Pattupattu anthologies, describes the process of making the flute. The holes in the bamboo tube were bored using red-hot embers. The flute is also mentioned in the Kurincippattu as the instrument on which the shepherds played the ambal pann. Among the other wind instruments were the Pili, a small trumpet and Kanvidutumbu a larger flute), perhaps producing lower octaves. The flute also acted as a drone providing a constant pitch for vocalists and other instruments 'as long as the trunk of an elephant'.

The Murasu, or the drum was the most popular percussion instrument. During festivals, the sound of Murasu conveyed joy and gaiety. Muzhavu, another percussion instrument accompanied singers. The drum was also used as the war-drum, calling people to arms. Mathuraikkanci mentions that the murasu was one of the prized possessions captured from the defeated enemy in the battlefield. Malaipatukatam describes the method of constructing and tuning the murasu. The sides were covered with skin, which were kept in position by leather straps. Malaipatukatam also mentions other percussion instruments such as udukkai, a palm-sized drum, Muzhavu, Siruparai and Tattai. The sound tattai resembled the croaking of a frog. This was a crude folk instrument made using a bamboo stick. Numerous slits were made across the stick and sound was produced on it by striking it on a stone or any other hard surface. In the Kurincippattu peasant women use tattai to scare the birds from the paddy field. A well-known percussion instrument is the mridangam (mathangam). It's a double headed drum used to accompany the veena (Yaazh) and the flute among other instruments.

List of Musical instruments used by ancient Tamil people was listed in Tirumurai dated between 6th and 11th century CE and include Akuli, Idakkai, Ilayam, Udukkai, Yezhil, Kathirikkai, Kandai, Karathalam, Kallalaku, Kalavadam, Kavil, Kazhal, Kalam, Kinai, Kinkini, Kilai, Kinnaram, Kudamuzha, Kuzhal, Kaiyalaku, Kokkarai, Kodukotti, Kottu, Kombu, Sangu, Sachari, Sanchalam, Salari, Siranthai, Silambu, Sinam, Thagunicham, Thakai, Thadari, Thattazhi, Thathalagam, Thandu, Thannumai, Thamarugam, Thaarai, Thaalam, Thuthiri, Thunthubi, Thudi, Thuriyam, Thimilai, Thondagam, Naral Surisangu, Padagam, Padutham, Panilam, Pambai, Palliyam, Parandai, Parai, Paani, Paandil, Pidavam, Perigai, Mathalam, Mani, Maruvam, Murasu, Muravam, Murugiyam, Murudu, Muzhavu, Monthai, Yaazl, Vangiyam, Vattanai, Vayir, Veenai, Veelai, and Venkural.