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Andrew Schally

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Andrew Schally

Andrzej Viktor "Andrew" Schally (30 November 1926 – 17 October 2024) was a Polish-American endocrinologist who was a co-recipient, with Roger Guillemin and Rosalyn Sussman Yalow, of the 1977 Nobel Prize in Physiology or Medicine. This award recognized his research in the discovery that the hypothalamus controls hormone production and release by the pituitary gland, which controls the regulation of other hormones in the body. Later in life, Schally utilized his knowledge of hypothalamic hormones to research possible methods for birth control and cancer treatment.

Andrzej Wiktor Schally was born in Wilno in the Second Polish Republic (now Vilnius, Lithuania) on 30 November 1926, the son of Brigadier General Kazimierz Schally, who was chief of the cabinet of President Ignacy Mościcki of Poland, and Maria (née Łącka). He was born into a Jewish family.

In September 1939, when Poland was attacked by Nazi Germany and the Soviet Union, Schally escaped with Poland's President Ignacy Mościcki, the prime minister and the whole cabinet to the neutral Romania, where they were interned [citation needed].

I was fortunate to survive the holocaust while living among the Jewish-Polish Community in Roumania. I used to speak Polish, Roumanian, Yiddish, Italian and some German and Russian, but I have almost completely forgotten them, and my French in which I used to excel is also now far from fluent.

Immediately after the war, in 1945, Schally moved via Italy and France to the United Kingdom where he changed his first name to Andrew. Schally received his education in Scotland and England. In 1952, he moved to Canada. He received his doctorate in endocrinology from McGill University in 1957. That same year he left for a research career in the United States where he has worked principally at Tulane University.

Schally conducted research in endocrinology at the Miami Veteran's Administration Medical Center in Miami, Florida.[citation needed] A Canadian citizen when he left Canada, Schally became a naturalized citizen of the United States in 1962. He was affiliated with the Baylor College of Medicine for some years in Houston, Texas.

By 1966 Schally had processed 100,000 Pigs brains to isolate 2.8 mg of thyrotropin-releasing hormone (TRH) developing a new realm of knowledge concerning the brain's control over the body chemistry. Schally explained in his 1977 Nobel Lecture that he, alongside his researchers, further dissected 250,000 porcine hypothalami in order to isolate 5 mg more of the hormone TRH to determine its molecular structure. His work also addressed birth control methods and the effects of growth hormones on the body. Together with Roger Guillemin he described the neurohormone gonadotropin-releasing hormone (GnRH) that controls follicle-stimulating hormone (FSH) and luteinizing hormone (LH), two hormones that are integral parts of reproduction and growth and development.

Schally received an honoris causa doctors degree from the Jagiellonian University in Kraków.

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