Annelies Marie Frank, known as Anne, was born in Frankfurt, Germany, to Otto Frank and Edith Hollander Frank. Her birth marked the beginning of a life that would tragically intersect with the rise of Nazism and the horrors of the Holocaust. The family, like many Jewish families in Germany, initially lived a comfortable and relatively assimilated life, but the growing antisemitism would soon force them to make difficult choices.

As the Nazi Party gained power in Germany and antisemitism intensified, Otto Frank made the difficult decision to move his family to Amsterdam, Netherlands, seeking refuge from the increasingly oppressive regime. This relocation was a desperate attempt to secure a safer future for Anne, her sister Margot, and his wife, Edith. Otto established a business in Amsterdam, hoping to rebuild their lives in a more tolerant environment.