Community hub
Recent from talks
Knowledge base stats:
Talk channels stats:
Members stats:
Arsenic trioxide
Arsenic trioxide is the inorganic compound with the formula As4O6. As an industrial chemical, its major uses include the manufacture of wood preservatives, pesticides, and glass. For medical purposes, it is sold under the brand name Trisenox among others when used as a medication to treat a type of cancer known as acute promyelocytic leukemia. For this use it is given by injection into a vein.
Arsenic trioxide was approved for medical use in the United States in 2000. It is on the World Health Organization's List of Essential Medicines. Approximately 50,000 tonnes were produced in 1991. Due to its toxicity, a number of countries have regulations around its manufacture and sale.
Arsenic trioxide is the dominant form of arsenic for commercial applications. Industrial uses include usage as a precursor to forestry products, in colorless glass production, and in electronics. Being the main compound of arsenic, the trioxide is the precursor to elemental arsenic, arsenic alloys, and arsenide semiconductors. Bulk arsenic-based compounds sodium arsenite and sodium cacodylate are derived from the trioxide.
A variety of applications exploit arsenic's toxicity, including the use of the oxide as a wood preservative. Copper arsenates, such as chromated copper arsenate, are derived from arsenic trioxide. These compounds were once used on a large scale as wood preservatives in the U.S. and Malaysia, but are now banned in many parts of the world. This practice remains controversial. When combined with copper(II) acetate, arsenic trioxide gives the vibrant green pigment known as Paris green, which finds some use as an insecticide.
Despite the well known toxicity of arsenic, arsenic trioxide was used in traditional Chinese medicine, where it is known as pi-shuang (Chinese: 砒霜; pinyin: pīshuāng; lit. 'arsenic frost'). Some discredited patent medicines, e.g., Fowler's solution, contained derivatives of arsenic oxide.
Arsenic trioxide is used to treat a type of cancer known as acute promyelocytic leukemia (APL). It may be used both in cases that are unresponsive to other agents, such as all-trans retinoic acid (ATRA) or as part of the initial treatment of newly diagnosed cases. This initial treatment may include combination therapy of arsenic trioxide with all-trans retinoic acid (ATRA).
Arsenic trioxide can be generated via routine processing of arsenic compounds including the oxidation (combustion) of arsenic and arsenic-containing minerals in air. Illustrative is the roasting of orpiment, a typical arsenic sulfide ore.
Smelting and related ore processing often generate arsenic trioxide, which poses a risk to the environment. For example, the Giant Mine in Canada processed substantial amounts of arsenopyrite-contaminated gold ores.
Hub AI
Arsenic trioxide AI simulator
(@Arsenic trioxide_simulator)
Arsenic trioxide
Arsenic trioxide is the inorganic compound with the formula As4O6. As an industrial chemical, its major uses include the manufacture of wood preservatives, pesticides, and glass. For medical purposes, it is sold under the brand name Trisenox among others when used as a medication to treat a type of cancer known as acute promyelocytic leukemia. For this use it is given by injection into a vein.
Arsenic trioxide was approved for medical use in the United States in 2000. It is on the World Health Organization's List of Essential Medicines. Approximately 50,000 tonnes were produced in 1991. Due to its toxicity, a number of countries have regulations around its manufacture and sale.
Arsenic trioxide is the dominant form of arsenic for commercial applications. Industrial uses include usage as a precursor to forestry products, in colorless glass production, and in electronics. Being the main compound of arsenic, the trioxide is the precursor to elemental arsenic, arsenic alloys, and arsenide semiconductors. Bulk arsenic-based compounds sodium arsenite and sodium cacodylate are derived from the trioxide.
A variety of applications exploit arsenic's toxicity, including the use of the oxide as a wood preservative. Copper arsenates, such as chromated copper arsenate, are derived from arsenic trioxide. These compounds were once used on a large scale as wood preservatives in the U.S. and Malaysia, but are now banned in many parts of the world. This practice remains controversial. When combined with copper(II) acetate, arsenic trioxide gives the vibrant green pigment known as Paris green, which finds some use as an insecticide.
Despite the well known toxicity of arsenic, arsenic trioxide was used in traditional Chinese medicine, where it is known as pi-shuang (Chinese: 砒霜; pinyin: pīshuāng; lit. 'arsenic frost'). Some discredited patent medicines, e.g., Fowler's solution, contained derivatives of arsenic oxide.
Arsenic trioxide is used to treat a type of cancer known as acute promyelocytic leukemia (APL). It may be used both in cases that are unresponsive to other agents, such as all-trans retinoic acid (ATRA) or as part of the initial treatment of newly diagnosed cases. This initial treatment may include combination therapy of arsenic trioxide with all-trans retinoic acid (ATRA).
Arsenic trioxide can be generated via routine processing of arsenic compounds including the oxidation (combustion) of arsenic and arsenic-containing minerals in air. Illustrative is the roasting of orpiment, a typical arsenic sulfide ore.
Smelting and related ore processing often generate arsenic trioxide, which poses a risk to the environment. For example, the Giant Mine in Canada processed substantial amounts of arsenopyrite-contaminated gold ores.