The Bukharan Quarter (Hebrew: שכונת הבוכרים, Shkhunat HaBukharim), also HaBukharim Quarter or Bukharim Quarter, is a neighborhood in the center of Jerusalem, Israel. The neighborhood was established by Bukharan Jews of the Old Yishuv. The neighborhood also anchored communities from modern-day Afghanistan and Iran. It belonged to the early Jewish neighborhoods built outside the Old City of Jerusalem as part of a process which began in the 1850s. Today most of the residents are Haredi Jews.

The quarter borders Tel Arza on the west, the Shmuel HaNavi neighborhood on the north, Arzei HaBira on the east, and Geula on the south.^{[citation needed]}

The current Chief Rabbi of the Bukharan Quarter is Rabbi Shlomo Kassin.

The first immigrants of Bukharan Jews from Russian Turkestan (Central Asia) settled in Jerusalem in the 1870s and 1880s. In 1890, seven members of the Bukharan Jewish community formed the Hovevei Zion Association of the Jewish communities of Bukhara, Samarkand and Tashkent. In 1891, the association bought land and drew up a charter stating that the new quarter would be built in the style of Europe's major cities. Architect Conrad Schick was employed to design the neighborhood. The streets were three times wider than even major thoroughfares in Jerusalem at the time, and spacious mansions were built with large courtyards. The homes were designed with neo-Gothic windows, European tiled roofs, neo-Moorish arches and Italian marble. Facades were decorated with Jewish motifs such as the Star of David and Hebrew inscriptions.

The founders named their settlement Rehovot based on a verse from the Hebrew Bible: "so (Isaac) called it Rehoboth [that is Broad places or Room], saying, "Now the Lord has made room for us, and we shall be fruitful in the land." (Genesis 26:22). It became also historically known as Bukhariyeh.

The neighborhood's Baba Tama Synagogue was built in 1894 and named for the Bukharan Jew who financed it.

In 1905-1908, a dairy was opened and cotton fields were planted on the outskirts of the neighborhood. Construction of the quarter continued into the early 1950s. A total of 200 houses were built. During World War I, the Ottoman army occupied several buildings and cut down almost all of the trees. In 1920, a factory for weaving Persian carpets opened, providing employment for 80 women.

Between 1953-1963, Rabbi Bernard M. Casper was working as Dean for Student Affairs at the Hebrew University of Jerusalem, and during this period he became deeply concerned about the impoverished Quarter. After his appointment as Chief Rabbi in South Africa he set up a special fund for the Quarter's improvement and this was tied with Prime Minister Menachem Begin's urban revitalization program, Project Renewal. Johannesburg was twinned with the Bukharan Quarter, and Johannesburg Jewry raised enormous funds for its rehabilitation. Frustrated by the lack of progress, Casper traveled to Jerusalem in 1981 to resolve the hurdles. He consulted with community organizer Moshe Kahan and suggested that they present the dormant agencies with concrete evidence of what could be done. Using a private discretionary fund, he initiated development of several pilot projects, among them a free loan fund, a dental clinic and a hearing center whose successes spurred the municipality back on track.