Catharine Littlefield Greene died of malaria at the Dungeness plantation on Cumberland Island, Georgia, at the age of 59. She was buried in the family cemetery there. Her death marked the end of a life marked by significant contributions to the American Revolution, plantation management, and support for technological innovation.

Catharine Greene married Phineas Miller, her children's tutor and the former plantation manager, in Philadelphia at the home of President George and Martha Washington. This marriage signified a new chapter in her life after the death of her first husband and marked her continued involvement in the management of plantation affairs.

Nathanael Greene, Catharine Littlefield Greene's first husband, died of sunstroke. This event led Catharine to assume responsibility for managing the plantation.

The Battles of Lexington and Concord, often regarded as the start of the American Revolutionary War. While this event did not directly involve Catharine Greene, it marked the beginning of the conflict that would significantly shape her life and bring her into close proximity with her husband's military activities.

Catharine Littlefield married Nathanael Greene, a fellow Rhode Islander and merchant, in Coventry, Rhode Island. This marriage marked a significant change in her life, leading her to become deeply involved in the American Revolutionary War efforts and later impacting her role in the plantation economy of the South.

Death of Phebe Ray Littlefield, Catharine Littlefield Greene's mother. She was buried in the Block Island Old Burial Ground in May.

Catharine Littlefield, later known as Catharine Littlefield Greene, was born on Block Island, Rhode Island. She was born to John Littlefield and Phebe Ray Littlefield. This marked the beginning of the life of a woman who would become known for her patriotism during the American Revolution and her support of Eli Whitney's cotton gin invention.