Chalisgaon (चाळीसगाव) pronunciation^ⓘ is second largest city and municipal council in Jalgaon district of the Indian state of Maharashtra. It is located in the Khandesh division of the state. and is located about 100 km (62 miles) from Jalgaon and about 330 km (210 miles) from Maharashtra's capital Mumbai.

Chalisgaon is located at 20°28′N 75°01′E / 20.47°N 75.02°E / 20.47; 75.02. It has an average elevation of 344 metres (1128 feet). It is situated around hills and the banks of the Titur River. The surrounding area is spread by wildlife forest.