Babbage married Georgiana Whitmore at St. Michael's Church in Teignmouth, Devon. Their marriage appears to have been a happy and supportive one.

Charles and Georgiana Babbage had eight children together. However, only three survived to adulthood: Benjamin Herschel Babbage, Georgiana Whitmore Babbage, and Henry Prevost Babbage.

Georgiana Babbage died, leaving Charles devastated. This loss marked a turning point in his life and likely contributed to his increasing focus on his scientific work.

Charles' father Benjamin also died in 1827. As the eldest son, Charles inherited a substantial estate from his father.

Following Georgiana's death, Babbage experienced the deaths of several of his children. The loss of his wife and children had a profound impact on him.

Babbage maintained relationships with his three surviving children, particularly Benjamin Herschel Babbage, who became a civil engineer in Australia, and Henry Prevost Babbage, who later worked on completing a portion of the Analytical Engine.

Charles Babbage died in London at the age of 79. He was buried in Kensal Green Cemetery. His contributions to science and mathematics were increasingly recognized posthumously.