The Clark County Board of County Commissioners, commonly referred to as the Clark County Commission, is the legislative body of Clark County in the U.S. state of Nevada. Established in 1909, the commission consists of seven members elected by district to four-year terms on a partisan basis. Although technically a legislative body, Nevada county commissions exercise powers of all three branches of government to varying degrees.

Powers and duties include law enforcement, administering state statute regarding health, marriage, divorce, child custody and property and exercises both executive powers throughout the county’s unincorporated areas including enacting ordinances, budgets, and oversees departments such as public works, fire protection, and social services.

The commission appoints the county manager to carry out the day-to-day operations of the Clark County government. As of 2025^[update], the commission is led by Tick Segerblom (D–District E) as chair and William McCurdy II (D–District D) as vice-chair.

Each commissioner is elected to a four-year term and represents one of seven districts, each designated a letter A through G.

The Clark County Commissioners as a group sit on the following boards, ex officio:

Concluding an investigation from 2002–2006 by the Federal Bureau of Investigation, four out of seven commissioners were convicted of multiple corruption charges on May 5, 2006. Former commissioners Dario Herrera, Erin Kenny, Mary Kincaid-Chauncey and Lance Malone were convicted of conspiracy and multiple counts of wire fraud and extortion under color of law for depriving the commission and the citizens of Clark County of their right to the honest services of public officials. They were sentenced to federal prison terms.