Iconology Inc., d/b/a ComiXology (styled comiXology), was a cloud-based digital distribution platform for comics owned by Amazon, with over 200 million comic downloads as of September 2013^[update]. At its height it offered a selection of more than 100,000 comic books, graphic novels, and manga across Android, iOS, Kindle Fire, Windows 10, and the Internet. In 2023, the ComiXology app was officially retired and the material was made available exclusively on the Amazon Kindle app.

ComiXology's digital platform with Guided View reading technology is used in the company's own branded applications, and is the engine used by most major comic book publishers in the United States, including Marvel Comics and DC Comics for their privately branded digital services. With the release of the third generation iPad and its Retina Display, ComiXology released a high-definition comic format dubbed CMX-HD. The company also provides tools for brick-and-mortar comic book retailers to participate in digital comic sales.

The company was founded in 2007 by CEO David Steinberger, CTO John D. Roberts, and Peter Jaffe. Subsequent to winning the business plan competition at New York University, the company received seed financing from Kit McQuiston, New York Angels and Rose Tech Ventures.

In April 2014, Amazon acquired Comixology for an undisclosed sum, which The Motley Fool argued was an attempt to control the comic book market after Amazon Publishing's Jet City Comics imprint failed to achieve major market share after its July 2013 launch.

In May 2016, the company launched ComiXology Unlimited, a subscription service that gives digital access to thousands of comics to read from most major publishers for a monthly fee of $5.99. The service offers more than four thousand issues to its subscribers and launched on May 24, 2016, with available content updated on a monthly basis. According to the company, the service offers the widest subscription selection of digital comics in the world. ComiXology Unlimited contains a selection of titles from Image Comics, Dark Horse, IDW Publishing, BOOM! Studios, Dynamite Entertainment, Kodansha Comics, Oni Press, Valiant Entertainment, Archie Comics, Fantagraphics Books, Humanoids, Action Lab Entertainment, Aspen Comics, Magnetic Press, Zenescope Entertainment and more. ComiXology Unlimited is currently limited to the U.S.

ComiXology's Guided View technology allows readers to read through comics in full screen or from panel-to-panel, mimicking the natural movement of the eye as though readers were experiencing reading a print comic book.

In June 2018, the company announced ComiXology Originals, an initiative to publish creator-owned titles.

During 2021 Amazon.com was to close the ComiXology website in a move to integrate ComiXology into Amazon Kindle, but was delayed to 2022, due to community feedback. During February 2022, the ComiXology website updated their FAQ on their website with new information to indicate the coming changes which were brought about on February 17, 2022, to which ComiXology is only available on Amazon.com or through their update to the ComiXology app that was done two days earlier on February 15, 2022.^{[citation needed]}