Course of Freedom (Greek: Πλεύση Ελευθερίας, romanized: Plefsi Eleftherias) is a Greek anti-establishment political party founded in 2016 by the former President of the Hellenic Parliament, Zoe Konstantopoulou.

On 19 April 2016, Zoe Konstantopoulou announced the founding of Course of Freedom. According to its founding declaration, the party's purpose of action consists of democracy, justice, transparency, rights, debt cancellation, and claim for World War II reparations.

Konstantopoulou, along with the party, had attended and called for support of the "Macedonia name" anti-Prespa Agreement mass protests of 2018 and 2019, with the slogan "I'm not ceding my homeland".

The party cooperates electorally with the I Don't Pay Movement, whose leaders were included in Course of Freedom's ballot to run in the European and Greek national elections of 2019.

Course of Freedom was able to enter the Hellenic Parliament at the June 2023 legislative election, scoring 3.17% and electing 8 members of Parliament.

The party condemned attacks on health facilities during the Gaza war after party president Konstantopoulou met with the Palestinian envoy, expressing her support for the Palestinian people; she vowed that Course of Freedom will "be the voice" of Palestine in Greece.

In the 2024 European election the party was able to elect one MEP, Maria Zacharia, who is a trade unionist and labourist.

Course of Freedom had a sitting Greek MP, Georgia Kefala, that participated in the March to Gaza and joined in the travel to Egypt.