The Crossroads League (formerly the Mid-Central College Conference) is a college athletic conference affiliated with the National Association of Intercollegiate Athletics (NAIA). Its members are private Christian colleges in Indiana, Michigan, and Ohio. The current conference commissioner is Larry DeSimpelare.

In June 2012, the conference voted to change its name to the Crossroads League, a name to better reflect the conference having grown beyond its Central Indiana roots.

The Crossroads League currently has ten full members; all are private, Christian schools:

The Crossroads had three former full members, all were private schools:

Full member (non-football) Full members (men only) Other Conference Other Conference

Each year, the member institution with the most points based on final rankings in each sport, is awarded the Commissioners Cup (formerly known as the All Sports Trophy). The current holder is Indiana Wesleyan University, which has won the last twelve cups in a row and holds the record for cups won, with eighteen.