The House of Zaccaria de Damalà—now Damalas— (Italian: Damalà, Greek: Δαμαλάς) is a formerly ruling family of Genoese origin, established in the 14th century on the Greek island of Chios, due to the marriage of Admiral Benedetto I Zaccaria with a sister of Byzantine Emperor Michael VIII Palaiologos; it later received the hereditary royal dignity of King and Despot of Asia Minor by grant of the Latin Emperor in 1325, and ultimately produced the last ruling dynasty of the Principality of Achaea in the 15th century.

After the dissolution of the family's Lordship of Chios in 1329, they concentrated their efforts on the Barony of Damalà in the Principality of Achaea, which they previously acquired through marriage to Jacqueline de la Roche, heiress of the Dukes of Athens. In time, they became the principality's last titled rulers, marrying in the process with other major houses ruling over Greek territories and in the Balkans, most notably, the Palaiologos, Asen and Tocco families. In the decades following the loss of their domains in the mid-15th century, the Zaccaria element of their name was gradually dropped, reduced to Damalà in reference to their former Achaean seat, and by the early 19th century, Hellenized to Damalas.

From the 15th to 20th centuries, the family maintained noble standing under Ottoman and Venetian dominion, particularly on Chios until its 1913 induction into the independent Kingdom of Greece, where they also held prominence since its 1832 founding through civic leadership, recurring royal association, and integration into aristocratic and political life. Their presence was also distinctly marked in the cities of Ermoupoli, Constantinople, Athens, and Piraeus, where they remained influential into the 20th century.

The Damalas that are descended from the Zaccaria dynasty share their name with other unrelated families of purely Byzantine origin and Orthodox faith, bearing the name Damalas, and who appear as early as 1230 in the Thracesian Theme of the Eastern Roman Empire. Descendants of these Greek families also settled on Chios and other nearby regions, and are often confused with the Genoese-descended Zaccaria de Damalà.

The connection of the Zaccaria name with that of Damalà began in the early 14th century, when Martino Zaccaria, then the third Genoese lord of Chios and Phocaea, received the Barony of Damalà in the Principality of Achaea, through his marriage to Jacqueline de la Roche; heiress of the founding dynasty of the Duchy of Athens.

Martino had four sons, Bartolomeo with his first, Venetian, Ghisi wife, and Centurione, Octaviano, and Manfredo with his second wife, Jacqueline de la Roche. Bartolomeo died in 1334, and though he had a daughter, Marulla, according to the Assizes of Romania, the Zaccaria family, as Latins in Frankish Greece, observed Salic Law which only allowed for male succession in their fiefdoms.

Thus his eldest brother Centurione succeeded him as Baron of Damalà; held by Bartolomeo since 1317. He was also given control of his father's other possessions in the Morea, sometime during Martino's imprisonment for having broken with Constantinople. This began the dynastic struggle of the Achaean baronies on the death of Philip of Taranto; the Latin Emperor ruling as Prince of Achaea.

According to the Chronicle of Morea, the original baronies were twelve, including Chalandritsa and Veligosti (Veligurt), whose fief was the argolid region of Damalà. After the fall of Veligosti around 1300, Damalà would become the seat of the barony, by then ruled by the Zaccaria.