Dara Shikoh (20 March 1615 – 30 August 1659), also transliterated as Dara Shukoh, was the eldest son and heir-apparent of the Mughal emperor Shah Jahan. Dara was designated with the title Padshahzada-i-Buzurg Martaba (lit. 'Prince of High Rank') and was favoured as a successor by his father and his elder sister, Princess Jahanara Begum. He had been given the title of 'Shah-e-Buland Iqbal' by Shah Jahan. In the war of succession which ensued after Shah Jahan's illness in 1657, Dara was defeated by his younger brother Prince Muhiuddin (later, the Emperor Aurangzeb). He was executed in 1659 on Aurangzeb's orders after a bitter struggle for the imperial throne.

Dara was a liberal-minded unorthodox Muslim as opposed to the orthodox Aurangzeb; he authored the work The Confluence of the Two Seas, which argues for the harmony of Sufi philosophy in Islam and Vedanta philosophy in Hinduism. A great patron of the arts, he was also more inclined towards philosophy and mysticism rather than military pursuits. The course of the history of the Indian subcontinent, had Dara Shikoh prevailed over Aurangzeb, has been a matter of some conjecture among historians.

Muhammad Dara Shikoh was born on 20 March 1615 in Ajmer, Rajasthan. He was the first son and third child of Prince Shahib-ud-din Muhammad Khurram and his second wife, Mumtaz Mahal. The prince was named by his father. 'Dara' means owner of wealth or star in Persian while the second part of the prince's name is commonly spelled in two ways: Shikoh (terror) or Shukoh (majesty or grandeur). Thus, Dara's full name can be translated as "Of the Terror of Darius" or "Of the Grandeur of Darius", respectively. Historian Ebba Koch favours 'Shukoh'.

Dara Shikoh had thirteen siblings of whom six survived to adulthood: Jahanara Begum, Shah Shuja, Roshanara Begum, Aurangzeb, Murad Bakhsh, and Gauhara Begum. He shared a close relationship with his sister, Jahanara. As part of his formal education, Dara studied the Quran, history, Persian poetry and calligraphy. He was a liberal-minded unorthodox Muslim unlike his father and his younger brother Aurangzeb. Persian was Dara's native language, but he also learned Hindi, Arabic and later Sanskrit.

In October 1627, Dara's grandfather Emperor Jahangir died, and his father ascended the throne in January 1628 taking the regnal name 'Shah Jahan'. In 1633, Dara was appointed as the Vali-ahad (heir-apparent) to his father. He and his older sister Jahanara were Shah Jahan's favourite children.

During the lifetime of his mother Mumtaz Mahal, Dara Shikoh was betrothed to his half-cousin, Princess Nadira Banu Begum, the daughter of his paternal uncle Sultan Parvez Mirza. He married her on 1 February 1633 at Agra amidst great celebrations, pomp and grandeur. By all accounts, Dara and Nadira were devoted to each other and Dara's love for Nadira was so profound that unlike the usual practice of polygyny prevalent at the time, he never contracted any other marriage. The imperial couple had seven children together; among them three sons, Sulaiman Shikoh, Mumtaz Shikoh, and Sipihr Shikoh, and a daughter, Jahanzeb Banu Begum, survived to play important roles in future events.

A great patron of the arts, Dara ordered for the compilation of some refined artwork into an album which is now famous by the name of 'Dara Shikoh Album'. This album was presented by Dara to his wife, Nadira Banu Begum, in 1641. It is one of the few Mughal albums that have their original miniatures, calligraphy, and original covers intact.

Dara had at least two concubines, Gul Safeh (also known as Rana Dil) and Udaipuri Mahal (a Georgian or Armenian slave girl). Udaipuri later became a part of Aurangzeb's harem after her master's defeat.