Delta Cafe is a Southern, cajun, and soul food restaurant in the Woodstock neighborhood of Portland, Oregon, United States. Anastasia Corya and Anton Pace opened the restaurant in 1995. They sold Delta in 2007 to open another Southern restaurant, Miss Delta, with two of the cafe's cooks. Frequented by Reed College students and neighborhood residents, Delta Cafe has been recognized as a favorite local comfort food destination. The cafe also has a cocktail bar called Delta Lounge. In 2016, a mural was painted on the restaurant's exterior as part of a neighborhood beautification project.

Delta Cafe is located on Woodstock Boulevard in southeast Portland's Woodstock neighborhood. Delta has been described as an "inexpensive neighborhood place" serving "generous" portions to Reed College students and having "a loyal following from all over". It originally had a single dining space and later expanded that to four. The restaurant plays "funky" music and has "odd" furniture and local art. It is open daily for a 9 am brunch, and from 5 to 10 pm for dinner, with the bar staying open later. As of 2011, the restaurant accepts cash and checks only.

The restaurant serves Southern, Cajun, and soul food. The menu includes fried chicken, fritters, hushpuppies, meatloaf, and ribs. Other options include fried versions of gizzards, okra, oysters, pickles, and shrimp. Since 2016, brunch has been served daily starting at 9 am. The brunch menu includes beignets, shrimp and grits, and smoked brisket hash

The bar, the Delta Lounge, stays open until 1 am on weekdays and 2 am on weekends. Drinks on Delta Lounge's menu include the Hey Ya!!!, a cucumber vodka cocktail; and a ginger drop made from ginger-infused vodka blended with lemon; as well as Bloody Marys and other cocktails that are also served with brunch.

Anastasia Corya and Anton Pace established Delta Cafe in 1995. Early on, Delta had a "symbiotic bar-restaurant relationship" with nearby Lutz Tavern, where guests on the waiting list for restaurant seating could wait at the bar. Before cell phones, Lutz staff would receive calls from Delta and announce when parties could be seated.

Corya and Pace sold the business in June 2007, then opened Miss Delta on Mississippi Avenue in north Portland in August 2007. Two of Delta Cafe's cooks, Jennifer Hazzard and Chuck Westmoreland, also became co-owners of Miss Delta and continued serving Southern cuisine. In 2012, Delta celebrated its seventeenth anniversary by offering forty-ounce Pabsts to patrons for $2.50, the price of the drink when the restaurant was founded.

In 2016, a mural was painted on the restaurant's west exterior as part of a neighborhood beautification initiative called the Woodstock Street Art Project. Funded in part by Metro and the Regional Arts & Culture Council, this and two other murals in the neighborhood were completed by Travis Czekalski and Jon Stommel, the art duo known as Rather Severe.

Delta began serving brunch daily in November 2016. The restaurant has also hosted Halloween and Mardi Gras celebrations.