The permissibility of depictions of Muhammad in Islam has been a contentious issue. Oral and written descriptions of Muhammad are readily accepted by all traditions of Islam, but there is disagreement about visual depictions. The Quran does not place any explicit or implicit prohibition on images of Muhammad. The ahadith (supplemental teachings) present an ambiguous picture, but there are a few that have prohibited Muslims from creating visual depictions of human figures. It is agreed on all sides that there is no authentic visual tradition (pictures created during Muhammad's lifetime) as to the appearance of Muhammad, although there are early legends of portraits of him, and written physical descriptions whose authenticity is often accepted.

The question of whether images in Islamic art, including those depicting Muhammad, can be considered as religious art remains a matter of contention among scholars. They appear in illustrated books that are normally works of history or poetry, including those with religious subjects; the Quran is never illustrated: "context and intent are essential to understanding Islamic pictorial art. The Muslim artists who created images of Muhammad, as well as the public who viewed them, understood that these images were not intended as objects of worship. Nor were the objects so decorated used as part of religious worship".

However, scholars concede that such images have "a spiritual element", and were also sometimes used in informal religious devotions celebrating the day of the Mi'raj. Many visual depictions only show Muhammad with his face veiled, or symbolically represent him as a flame; other images, notably from before about 1500, show his face. With the notable exception of modern-day Iran, depictions of Muhammad were never numerous in any community or era throughout Islamic history, and appeared almost exclusively in the private medium of Persian and other miniature book illustration. The key medium of public religious art in Islam was and is calligraphy. In Ottoman Turkey the hilya developed as a decorated visual arrangement of texts about Muhammad that was displayed as a portrait might be.

Visual depictions of Muhammad have always been rare in the non-Islamic West. In the Middle Ages they were mostly hostile, and most often appear in illustrations of Dante's poetry. In the Renaissance and Early Modern period, Muhammad was sometimes depicted, typically in a more neutral or heroic light; the depictions began to encounter protests from Muslims. In the age of the Internet, a handful of caricature depictions printed in the European press have caused global protests and controversy and been associated with violence.

In Islam, although nothing in the Quran explicitly bans images, some supplemental hadith explicitly ban the drawing of images of any living creature; other hadith tolerate images, but never encourage them. Hence, most Muslims avoid visual depictions of any prophet or messenger such as Muhammad, Moses, and Abraham.

Most Sunni Muslims believe that visual depictions of all the prophets and messengers should be prohibited and are particularly averse to visual representations of Muhammad. The key concern is that the use of images can encourage shirk or "idolatry". In Shia Islam, however, images of Muhammad are quite common nowadays even though historically, Shia scholars opposed such depictions. Still, many Muslims who take a stricter view of the supplemental traditions will sometimes challenge any depiction of Muhammad, including those created and published by non-Muslims.

Many major religions have experienced times during their history when images of their religious figures were forbidden. In Judaism, one of the Ten Commandments states "Thou shalt not make unto thee any graven image", while in the Christian New Testament all covetousness (greed) is defined as idolatry. During the periods of Byzantine Iconoclasm in the eighth century, and again during the ninth century, visual representations of sacred figures were forbidden by the Ecumenical Patriarchate of Constantinople, and only the Christian cross could be depicted in churches. The visual representation of Jesus and other religious figures remains a concern in parts of stricter Protestant Christianity.

Several ahadith and other writings of the early Islamic period include stories in which portraits of Muhammad appear. Abu Hanifa Dinawari, ibn al-Faqih, Ibn Wahshiyya, and Abu Nu'aym al-Isfahani tell versions of a story in which the Byzantine Emperor Heraclius is visited by two Meccans. He shows them a cabinet, handed down to him from Alexander the Great and created by God for Adam, each of whose drawers contains a portrait of a prophet. They are astonished to see a portrait of Muhammad in the final drawer. Sadid al-Din al-Kazaruni tells a similar story in which the Meccans are visiting the king of China. Al-Kisa'i tells that God did indeed give portraits of the prophets to Adam.