Deusto, also known as Deustu in Basque and formerly known as San Pedro de Deusto, is one of the eight districts of Bilbao, Spain. It is located on the right side of the Bilbao estuary, in the northwestern part of the city and bordering the estuary itself on the south and the southern hillside of Mount Artxanda and Mount Bandera on the north. Deusto was originally an elizate and also a municipality until 1925 when it was completely annexed by Bilbao in order to expand the free land available to the city. Deusto is known as the university district of the city as it is home to the University of Deusto and the Faculty of Economics and Business of the University of the Basque Country.

Little is known about the history of Deusto, as much of the local archives were destroyed during the Spanish Civil War. The exact moment of its foundation is unknown, but this is a common trait shared with other elizates across Biscay. It is known that the San Pedro de Deusto church was constructed some time around the 14th century and that until the 1700s the land was sparsely populated and the main economic activities were fishing and agricultural production, mostly wheat and vines.

The first town hall was erected in 1752, replaced by another building in 1888; this latter was demolished during the civil war. The town had the seat number 35 in the General Councils of Biscay. Traditionally, the municipality was divided into two quarters: Erribera (riverside) located by the river, which concentrated the commercial and maritime activities of the village, and Goierri (highland) at the foothills of mount Artxanda, which included most of the farm land. At the end of the 19th century the town enjoyed relative commercial prosperity thanks to the opening the railway line between Bilbao and Getxo, which included a station in Deusto. Using the railway line, many of the agricultural products from Deusto were more easily sold in the Ribera market of Bilbao.

A royal decree signed on 29 October 1924 established the annexation of Deusto to the city of Bilbao, effective on 1 January of the following year. Alongside Deusto, the elizates of Begoña and Lutxana were also annexed, although the latter would regain its autonomy in the early 1980s. In the following years a series of urban plans were developed, designed by architect Ricardo Bastida, with the aim of establishing a first urban grid for the district, which at the time still consisted mostly of scattered farmhouses. The rapid industrial development of Bilbao caused a massive migration of workers coming from elsewhere in Spain, and in consequence the creation of decadent shanty towns on the hills of the mount Banderas. These were demolished and replaced by apartment building projects in the decade of 1950, completely depleting the available land in the district.

The Deusto Bridge, a moveable bridge spanning the Bilbao estuary and connecting Deusto with Abando was constructed between 1932 and 1936. During the Francoist dictatorship it was renamed Bridge of the Generalissimo. Its name was changed back to Deusto in the late 1970s. In 1968 a canal was excavated connecting to the estuary on its northwestern side, with the aim of relieving the vessel traffic on the river. This canal became known as the Deusto Canal, and the newly created peninsula was named Zorrotzaurre. This peninsula would later become an artificial island, following the completion of the Zorrotzaurre Master Plan designed by architect Zaha Hadid. As part of the Plan, the canal was finished and officially opened on 8 October 2018, making the former peninsula become an island.

Deusto is located on the right bank of the estuary of Bilbao, on a plain between the river and nearby mountains. It borders to the north with Mount Artxanda, a natural border between the city of Bilbao and the neighbouring municipalities of Erandio and Sondika. To the east it borders the district of Uribarri, Abando to the south and Basurtu-Zorrotza to the west. Deusto has a total area of 4.95 square kilometres (2 sq mi).

Politically and administratively, the district of Deusto is subdivided into four quarters (Basque: auzo), although it is common for locals to refer to even smaller subdivisions. The quarters are Arangoiti, Ibarrekolanda, San Ignazio-Elorrieta and Deustu Doneperiaga-Deustuibarra. While Zorrotzaurre is administratively part of Deustu Doneperiaga-Deustuibarra, it is often considered as a separate entity due to its particular conditions.

The district of Deusto is popularly known as the university district of Bilbao. Located in Deusto is the main campus of the University of Deusto, a private university owned by the Society of Jesus, a religious order of the Catholic church. The university was founded in 1886 after the Jesuits moved their School of Higher Studies from Laguardia to its current location in Deusto. Since its foundation the university has played a prominent role in the industrial development of Bilbao and its metropolitan area. The main campus building was designed by Spanish architect Francisco de Cubas and it was the largest building of the city when it first opened.