Deuterated methanol (CD₃OD) is a form (called an isotopologue) of methanol (CH₃OH) in which the hydrogen atoms ("H") are replaced with deuterium (heavy hydrogen) isotope ("D"). Deuterated methanol is a common solvent used in NMR spectroscopy.

Deuterated methanol was first detected in interstellar space in the Kleinmann–Low Nebula in 1988 by scientists at the Max Planck Institute for Radio Astronomy.