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The Eastern Continental Divide, Eastern Divide or Appalachian Divide is a hydrological divide in eastern North America that separates the easterly Atlantic Seaboard watershed from the westerly Gulf of Mexico watershed. It is one of six continental hydrological divides of North America which define several drainage basins, each of which drains to a particular body of water.

The divide nearly spans the United States from south of Lake Ontario through the Florida peninsula, and consists of raised terrain including the Appalachian Mountains to the north, the southern Piedmont Plateau and lowland ridges in the Atlantic Coastal Plain to the south.

The divide's northern portion winds through the middle of the Appalachian Mountains, either through the interior of the Allegheny Plateau or along the Allegheny Mountains. In this portion, the western drainage of the divide flows into the watersheds of the Allegheny River, Monongahela River, and New River, all tributaries of the Ohio River. The eastern drainage flows into the watersheds of the Susquehanna River, Potomac River, and James River, all of which flow into the Chesapeake Bay before entering the Atlantic Ocean.

At its northern terminus, the Eastern Continental Divide originates at Triple Divide Peak in Ulysses Township, Pennsylvania, about 10 mi (16 km) south of the New York-Pennsylvania border, where it diverges from the St. Lawrence Divide. This point divides the eastern United States into three watersheds: those of the Genesee River flowing into Lake Ontario and then the St. Lawrence River to the north; Pine Creek into the Susquehanna River as part of the Atlantic seaboard watershed to the east; and the Allegheny River into the Ohio, the Mississippi, and the Gulf of Mexico to the west.

From north to south, the divide passes through the broader Allegheny Plateau region, following the boundary between the Allegheny River and Susquehanna River watersheds through most of Pennsylvania. At Blue Knob near Altoona, the Divide begins to follow Allegheny Mountain and then Little Savage Mountain. A few miles before the state border, the Divide begins to separate the Youghiogheny River and Potomac River watersheds.

In Maryland, the Divide runs significantly west of the Allegheny Front, following Backbone Mountain, and passing near the source of the North Branch Potomac River at the Fairfax Stone. The Divide then passes through a plateau of the Allegheny Mountains of West Virginia, passing between the north end of the Canaan Valley in the Cheat River watershed, and the Mount Storm Lake basin in the Potomac River watershed. The Divide then rejoins the Allegheny Front.

A significant portion of the Divide forms part of the border between West Virginia and Virginia along Allegheny Mountain and then Peters Mountain, separating the Greenbrier River and James River watersheds. It then makes a dramatic arc to the east around the Sinking Creek valley, and then follows the hill crest east of Blacksburg, Virginia.