Edward Stephenson Gamble (born 10 March 1986) is an English comedian, podcaster and television personality. He is best known for co-presenting the Off Menu podcast with James Acaster and appearances on comedy panel shows including Mock the Week and Taskmaster. He studied at Hatfield College, Durham University, where he began his comedy career performing with the Durham Revue, and was a finalist in the 2007 Chortle Student Comedy Awards.

Gamble was brought up in Wandsworth and Raynes Park, southwest London. His mother, a nurse and health visitor for the NHS, and father, a solicitor, separated when he was four; he was raised mainly by his mother. He has a younger half-sister and a younger half-brother on his father's side.

He attended Highfield School and Nursery in Wandsworth and later King's College School, a private day school for boys in Wimbledon. At school, he "used humour as a defence mechanism". He said that "there's no way that people could make jokes about my weight if I was making them myself, faster and better. Aside from losing weight, this was the best way to ward off bullying, and there was no way I was going to lose weight. I loved food."

He attended Durham University, where he studied philosophy and met fellow comedians Nish Kumar, Nick Mohammed, and Tom Neenan. He was a member of Hatfield College.

Before working full-time as a comedian, Gamble worked jobs which included short stints of manual labouring, data entry, and working at the Raynes Park Tavern (since refurbished), a pub that was "surprisingly dangerous for the area" and "on more than one occasion when I arrived for work there was an ambulance parked outside. (...) One night I arrived for work and literally had to step over a pool of blood outside the door."

Gamble's early work was alongside Ray Peacock, with whom he presented two different series of The Peacock and Gamble Podcast, totalling over 100 episodes. He also appeared on television, performing a 15-minute set on the extended version of Russell Howard's Good News on BBC Three in late 2010. He performed with Peacock at the Edinburgh Festival Fringe in 2011, 2012 and 2013, as well as supporting Greg Davies on his successful Firing Cheeseballs at a Dog Tour in 2011. Gamble also recorded a series of radio shows with Peacock on FUBAR Radio.

In 2014, Gamble debuted solo at Edinburgh Fringe with the show Gambletron 5000, returning in 2015 with Lawman and in 2016 with Stampede. His stand-up performances contain much observational comedy, often aimed at himself, including discussion of his Type 1 diabetes, which he was diagnosed with at 13; he chose that as the central topic of his 2018 Edinburgh Fringe show Blizzard and his Amazon Prime Video special Blood Sugar.^{[citation needed]}

Gamble was a regular panellist on the BBC panel show Mock the Week from July 2015. In the same year, he appeared with Amy Hoggart in Almost Royal, a faux-reality show on BBC America, in which the two portrayed aristocratic siblings Georgie and Poppy Carlton. The first series aired on E4 in the UK and was followed by a second series in 2016. He guest-hosted the Elis James and John Robins Show on Radio X in 2017 and 2018. Since 2018, Gamble has presented the podcast Off Menu with Ed Gamble and James Acaster with fellow comedian James Acaster as well as a weekly Radio X show with Matthew Crosby since 2019.^{[citation needed]}