The history of Jews in Europe spans a period of over two thousand years. Jews, a Semitic people descending from the Judeans of Judea in the Southern Levant, began migrating to Europe just before the rise of the Roman Empire (27 BCE), although Alexandrian Jews had already migrated to Rome, and some Gentiles had undergone Judaization on a few occasions. A notable early event in the history of the Jews in the Roman Empire was the 63 BCE siege of Jerusalem, where Pompey had interfered in the Hasmonean civil war.

Jews have had a significant presence in European cities and countries since the fall of the Roman Empire, including Italy, Spain, Portugal, France, the Netherlands, Germany, Poland, and Russia. In Spain and Portugal in the late fifteenth century, the monarchies forced Jews to either convert to Christianity or leave and they established offices of the Inquisition to enforce Catholic orthodoxy of converted Jews. These actions shattered Jewish life in Iberia and saw mass migration of Sephardic Jews to escape religious persecution. Many resettled in the Netherlands and re-judaized, starting in the late sixteenth and early seventeenth centuries. In the religiously tolerant, Protestant Dutch Republic Amsterdam prospered economically and as a center of Jewish cultural life, the "Dutch Jerusalem". Ashkenazi Jews lived in communities under continuous rabbinic authority. In Europe Jewish communities were largely self-governing autonomous under Christian rulers, usually with restrictions on residence and economic activities. In Poland, from 1264 (from 1569 also in Lithuania as part of the Polish–Lithuanian Commonwealth), under the Statute of Kalisz until the partitions of the Polish–Lithuanian Commonwealth in 1795, Jews were guaranteed legal rights and privileges. The law in Poland after 1264 (in the Polish–Lithuanian Commonwealth in consequence) toward Jews was one of the most inclusive in Europe. The French Revolution removed legal restrictions on Jews, making them full citizens. Napoleon implemented Jewish emancipation as his armies conquered much of Europe. Emancipation often brought more opportunities for Jews and many integrated into larger European society and became more secular rather than remaining in cohesive Jewish communities.

The pre-World War II Jewish population of Europe is estimated to have been close to nine million, or 57% of the world's Jewish population. Around six million Jews were killed in the Holocaust, which was followed by the emigration of much of the surviving population.

The Jewish population of Europe in 2010 was estimated to be approximately 1.4 million (0.2% of the European population), or 10% of the world's Jewish population. In the 21st century, France has the largest Jewish population in Europe, followed by the United Kingdom, Germany, Russia and Ukraine. Prior to the Holocaust, Poland had the largest Jewish population in Europe, as a percentage of its population. This was followed by Lithuania, Hungary, Latvia and Romania.

Hellenistic Judaism, originating from Alexandria, was present throughout the Roman Empire even before the Jewish–Roman wars. Large numbers of Jews lived in Greece (including the Greek isles in the Aegean and Crete) as early as the beginning of the 3rd century BCE. The first recorded mention of Judaism in Greece dates from 300 to 250 BCE, on the island of Rhodes. In the wake of Alexander the Great's conquests, Jews migrated from the Middle East to Greek settlements in the Eastern Mediterranean, spurred on by the opportunities they expected. As early as the middle of the 2nd century BCE, the Jewish author of the third book of the Oracula Sibyllina, addressing the "chosen people", says: "Every land is full of thee and every sea." The most diverse witnesses, such as Strabo, Philo, Seneca, Cicero, and Josephus, all mention Jewish populations in the cities of the Mediterranean Basin. Most Jewish population centers of this period were, however, still in the Levant, and Alexandria in Egypt was by far the most important of the Jewish communities, with the Jews in Philo's time inhabiting two of the five sections of the city. Nevertheless, a Jewish community is recorded to have existed in Rome at least since the 1st century BCE, although there may even have been an established community there as early as the second century BCE, for in the year 139 BCE, the praetor Hispanus issued a decree expelling all Jews who were not Roman citizens.

At the commencement of the reign of Caesar Augustus in 27 BCE, there were over 7,000 Jews in Rome: this is the number that escorted the envoys who came to demand the deposition of Archelaus. The Jewish historian Josephus confirms that as early as 90 CE there were two Israelite tribes living in Europe, Judah and Benjamin. Thus, he writes in his Antiquities: " ...there are but two tribes in Asia Minor and Europe subject to the Romans, while the ten tribes are beyond Euphrates till now and are an immense multitude." According to E. Mary Smallwood, the appearance of Jewish settlements in southern Europe during the Roman era was probably mostly a result of migration due to commercial opportunities, writing that "no date or origin can be assigned to the numerous settlements eventually known in the west, and some may have been founded as a result of the dispersal of Judean Jews after the revolts of CE 66–70 and 132–135, but it is reasonable to conjecture that many, such as the settlement in Pozzuoli attested in 4 BCE, went back to the late republic or early empire and originated in voluntary emigration and the lure of trade and commerce."

Many Jews migrated to Rome from Alexandria as a result of the close trade relations between the two cities. When the Romans captured Jerusalem in 63 BCE, thousands of Jewish prisoners of war were brought from Judea to Rome, where they were sold into slavery. Following the capture of Jerusalem by the forces of Herod the Great with assistance from Roman forces in 37 BCE, it is likely that Jews were again taken to Rome as slaves. It is known that Jewish war captives were sold into slavery after the suppression of a minor Jewish revolt in 53 BCE, and some were probably taken to southern Europe. After the enslaved Jews gained their freedom, they permanently settled in Rome on the right bank of the Tiber as traders, and some immigrated north later.

Despite their geographic dispersal, the diaspora Jews maintained ties with the Land of Israel, embarking on pilgrimages and making voluntary donations to the Temple via the half-shekel tax. Following the destruction of the Temple in 70 CE, this internal contribution was replaced by the fiscus Judaicus, a coerced Roman tax redirected toward the construction and maintenance of the Temple of Jupiter Optimus Maximus in Rome. Separately, they also sent charitable contributions to the Nesi'im in Israel, in accordance with Roman law, until the late fourth century as Byzantine leadership reversed course.