Frybread (also spelled fry bread) is a dish of the Indigenous people of North America that is a flat dough bread, fried or deep-fried in oil, shortening, or lard.

Made with simple ingredients, generally wheat flour, water, salt, and sometimes baking powder, frybread can be eaten alone or with various toppings, such as honey, jam, powdered sugar, venison, or beef. It is the base for Indian tacos.

Frybread has a complex cultural history that is inextricably intertwined with colonialism and displacement of Native Americans. The ingredients for frybread were provided to Native Americans to prevent them from starving when they were moved from areas where they could grow and forage their traditional foods to areas that would not support their traditional foods. Critics see the dish as both a symbol of colonization and a symbol of resilience.

According to Navajo tradition, frybread was created in 1864 using the flour, sugar, salt and lard that was given to them by the United States government when the Navajo, who were living in Arizona, were forced to make the 300-mile journey known as the "Long Walk" and relocate to Bosque Redondo, New Mexico, onto land that could not easily support their traditional staples of vegetables and beans. To prevent the displaced Native Americans from starving, the United States government provided a small set of staple food items, which included the ingredients with which to create a simple quick bread which was cooked in a pan of hot lard over coals and became known as frybread. The food eventually spread to other tribes. Boarding schools also helped to spread frybread in Native American diets.

Frybread was named the official state bread of South Dakota in 2005. That same year, activist Suzan Shown Harjo wrote a piece against frybread in Indian Country Today, calling the dish "emblematic of the long trails from home and freedom to confinement and rations...It's the connecting dot between healthy children and obesity, hypertension, diabetes, dialysis, blindness, amputations, and slow death"; critics have accused Harjo of overstating her case and unfairly blaming frybread for problems facing Native Americans. In 2012 the Phoenix restaurant The Fry Bread House was named an American Classic by the James Beard Foundation.

Frybread became inextricably intertwined with Native American culture and feelings toward colonialization and displacement, and also with pride in the resilience of a people and culture.

According to Smithsonian Magazine, for many Native Americans, "frybread links generation with generation and also connects the present to the painful narrative of Native American history".

Frybread's significance to Native Americans has been described as complicated and their relationship with it conflicted. Although frybread is often associated with "traditional" Native American cuisine, some Native American chefs reject it as a symbol of colonialism. Indigenous chef Sean Sherman calls it "everything that isn't Native American food", writing that it represents "perseverance and pain, ingenuity and resilience". Frybread became a symbol of resilience as it was developed out of necessity using government-provided flour, sugar, and lard. However, indigenous chefs such as Sherman consider it a symbol of colonial oppression, as the ingredients were being provided because the government had moved the people onto land that could not support growing traditional staples like corn and beans.