Civil unrest over the murder of George Floyd began as local protests in Minneapolis–Saint Paul on May 26, 2020, the day after George Floyd was killed by a Minneapolis police officer. Protests and civil disorder quickly spread to other locations in the U.S. state of Minnesota, the United States, and internationally. This list includes notable protests and events of civil disorder in Minnesota in the aftermath of Floyd's murder.

On June 2, hundreds of protesters rallied for police accountability in Albert Lea at the Freeborn County Courthouse and then marched around town despite severely hot weather. Director of Public Safety JD Carlson told protesters that he did not support Chauvin's actions against Floyd in Minneapolis, and offered an open door between the community and the police department. Freeborn County Sheriff Kurt Freitag expressed concern for the protesters, and recommended that they come prepared with water and sun protection if protesting in summer.

On June 1, dozens of protesters gathered near the Rum River Bridge to peacefully protest the murder of George Floyd. Anoka County Sheriff James Stuart spoke in support of the protest. Several local officials attended the event, including Minnesota State Senator Jim Abeler.

On May 29, during the early morning hours, Minnesota residents Fornandous Cortez Henderson of Savage and Garrett Ziegler of Long Lake attacked the Dakota County Western Service Center in Apple Valley—a local government building that contained a U.S. passport office, court rooms, and other official services. Henderson had targeted the building as revenge for the appearances he made before a court located inside it and because he was angry with law enforcement over Floyd's murder. The two men broke several windows with baseball bats and threw Molotov cocktails inside. Some of the incendiary devices ignited and caused fire and smoke damage. The men also poured flammable liquids around the building and attempted to start other fires. Law enforcement that responded to a building alarm arrested Ziegler and Henderson as they fled on foot.

On May 31, approximately 300 protesters rallied at Bandshell Community Park in Austin and marched to the law enforcement center before returning to the park and disbanding. Another protest occurred on the July 25.^{[citation needed]}

On May 30, between 300 and 500 protesters marched from Paul Bunyan Park to the Bemidji Police Department; the demonstration was peaceful until some protesters attacked a D.A.R.E. truck, which then backed into a crowd of demonstrators and mildly injured an event volunteer. After the protest, mayor Rita Albrecht signed a declaration of a curfew between 8:00 p.m. and 6:00 a.m.

On July 5, the 10K Foundation organized a march from the Mall of America in Bloomington to the George Floyd memorial site in downtown Minneapolis.

On May 29, over 60 people gathered at a busy intersection in Brainerd to support Black Lives Matter and protest the murder of George Floyd.