Guge (Tibetan: གུ་གེ་, Wylie: gu ge) was an ancient dynastic kingdom in Western Tibet. The kingdom was centered in present-day Zanda County, Ngari Prefecture, Tibet Autonomous Region. At various points in history after the 10th century AD, the kingdom held sway over a vast area including south-eastern Zanskar, Kinnaur district, and Spiti Valley, either by conquest or as tributaries. The ruins of the former capital of the Guge kingdom are located at Tsaparang in the Sutlej valley, not far from Mount Kailash and 1,200 miles (1,900 km) west from Lhasa.

Guge was founded in the 10th century. Its capitals were located at Tholing 31°28′55″N 79°48′01″E / 31.48194°N 79.80028°E / 31.48194; 79.80028 and Tsaparang. Kyide Nyimagon, a great-grandson of Langdarma, the last monarch of the Tibetan Empire, fled to Ngari (West Tibet) from the insecure conditions in Ü-Tsang in 910. He established a kingdom around 912, annexing Purang and Guge. He established his capital in Guge.

Nyimagon later divided his lands into three parts. The king's eldest son Palgyigon became ruler of Maryul (Ladakh), his second son Trashigon (bKra shis mgon) received Guge-Purang, and the third son Detsukgon received Zanskar.

Trashigon was succeeded by his son Srong nge or Yeshe-Ö (Ye shes 'Od) (947–1024 or (959–1036), who was a renowned Buddhist figure. In his time a Tibetan lotsawa from Guge called Rinchen Zangpo (958–1055), after having studied in India, returned to his homeland as a monk to promote Buddhism. Together with the zeal of Yeshe-Ö, this marked the beginning of a new diffusion of Buddhist teachings in western Tibet. In 988 Yeshe-Ö took religious vows and left kingship to his younger brother Khor re.

According to later historiography, the Turkic Karluks (Gar log) took the Yeshe-Ö prisoner in a war. The episode has a prominent place in Tibetan history writing. The Karluks offered to set him free if he renounced Buddhism, which he refused to do. They then demanded his weight in gold to release him. His junior kinsman Byang chub 'Od visited him in his prison with a small retinue, but Yeshe-Ö admonished him not to use the gold at hand for ransom, but rather to invite the renowned Mahayana sage Atiśa (982–1054). Yeshe-Ö eventually died in prison from age and poor treatment. The story is historically debated since it contains chronological inconsistencies.^{[citation needed]}

In 1037, Khor re's eldest grandson 'Od lde was killed in a conflict with the Kara-Khanid Khanate from Central Asia, who subsequently ravaged Ngari. His brother Byang chub 'Od (984–1078), a Buddhist monk, took power as secular ruler. He was responsible for inviting Atiśa to Tibet in 1040 and thus ushering in the so-called Chidar (Phyi-dar) phase of Buddhism in Tibet. Byang chub 'Od's son rTse lde was murdered by his nephew in 1088. This event marked the break-up of the Guge-Purang kingdom, since one of his brothers was established as separate king of Purang. The usurping nephew dBang lde continued the royal dynasty in Guge.

A new Kara-Khanid invasion of Guge took place before 1137 and cost the life of the ruler, bKra shis rtse. Later in the same century the kingdom was temporarily divided. In 1240 the Mongol khagan, at least nominally, gave authority over the Ngari area to the Drigung Monastery in Ü-Tsang.

Grags pa lde was an important ruler who united the Guge area around 1265 and subjugated the related Ya rtse (Khasa) kingdom. After his death in 1277 Guge was dominated by the Sakya monastic regime. After 1363, with the decline of the Mongol-led Yuan dynasty and their Sakya protégés, Guge was again strengthened and took over Purang in 1378. Purang was henceforth contested between Guge and Mustang, but was finally integrated into the former. Guge also briefly ruled over Ladakh in the late 14th century. From 1499 the Guge king had to acknowledge the Rinpungpa rulers of Tsang. The 15th and 16th centuries were marked by a considerable Buddhist building activity by the kings, who frequently showed their devotion to the Gelug leaders later known as the Dalai Lamas.