Henriette Wyeth Hurd (October 22, 1907 – April 3, 1997) was an American artist noted for her portraits and still life paintings. The eldest daughter of illustrator N.C. Wyeth, she studied painting with her father and brother Andrew Wyeth at their home and studio in Chadds Ford, Pennsylvania.

After she and artist Peter Hurd married, they moved to San Patricio, New Mexico, in the mid-1930s and raised their three children on a ranch there. They were both inspired by the landscape and eventually had a 2200-acre ranch. One of her well-known quotes is: "I don't know what is important and what is unimportant, so I call it all immensely important."

Henriette Wyeth was born in Wilmington, Delaware, into an artistic family. Wyeth was the eldest of the five children of noted illustrator N.C. Wyeth and his wife Carolyn Bockius. Her siblings Carolyn and Andrew also became artists, and all three studied with their father. Andrew Wyeth became the most well-known artist of this family.

Henriette contracted polio at age 3, which altered her health and use of her right hand. As a result, she learned to draw with her left hand and paint with her right. She grew up on the family farm in Chadds Ford, Pennsylvania, and attended local Quaker schools. She and her siblings were eventually homeschooled because their father distrusted the public school system. She began formal art lessons with her father at age 11, making charcoal studies and geometric shapes.

A child prodigy, at age 13 Wyeth was enrolled in the Normal Arts School in Boston, Massachusetts. The next year, in 1921, she entered the Boston Museum of Art Academy. Two years later she moved to Philadelphia to study painting at the Pennsylvania Academy of Fine Arts. By age 16, she was well known as a portraitist and received commissions for paintings of Wilmington residents. Deeply influenced by her father's unique realistic style, she rejected early 20th-century painting styles such as Impressionism and Cubism. She was also socially and politically conservative. As a result, later in life she rejected the progressive movements of the 1960s and 1970s, including the women's movement. She often criticized television and modern culture.

Soon after her student years, Hurd exhibited at the Pennsylvania Academy (1927, 1936–44), where she was awarded the 1937 Mary Smith Prize for a portrait of her son Peter. Wyeth's work spanned portraits of adults and children, still lifes, and floral landscapes. In her work, she "often included objects that related to the subject's interest or personality". She eventually stopped painting children because, as she said, "today's children--they are so deadpan."

She painted for Helen Hayes, Paulette Goddard, and Mrs. John D. Rockefeller III (Blanchette Hooker Rockefeller), for which she earned a lasting celebrity. In 1963, she painted a portrait of her brother Andrew for the cover of Time magazine. Hurd and Wyeth were both commissioned to produce a cover portrait of President Lyndon B. Johnson for Time's "Man of the Year" issue. She received awards for her work, including the Governor's Award in New Mexico and a Living Legacy Award from the Women's International Center.

Her most widely known work is the official White House portrait of First Lady Pat Nixon.