Hessenheim (French pronunciation: [esənaim]) is a commune in the Bas-Rhin department in Alsace in north-eastern France.

Hessenheim lies just over twelve kilometres (eight miles) to the southeast of Sélestat. To the south is the commune of Heidolsheim; Marckolsheim is across the canal to the east. On the eastern side, the commune's territory is bordered by the Rhône-Rhine Canal, which here runs parallel with but approximately four kilometres to the west of the river Rhine itself and the German frontier.

The economy is based on agriculture: an important ingredient in that is livestock rearing. To the north of the village is the so-called Hessenheimer Pasture land, though most of this is within the adjacent commune of Mussig.