Holy Bull (January 24, 1991 – June 7, 2017) was a champion Thoroughbred racehorse. Although he finished a disappointing twelfth in the 1994 Kentucky Derby, his major wins that year in the Florida Derby, Blue Grass Stakes, Metropolitan Handicap, Haskell Invitational, Travers Stakes and Woodward Stakes earned him American Horse of the Year honors. He suffered a career-ending injury in the Donn Handicap soon after the beginning of his four-year-old campaign in 1995.

Subsequently, retired to stud, he was the sire of Kentucky Derby winner Giacomo and champion two-year-old Macho Uno.

Holy Bull was ranked #64 on the Blood-Horse magazine's list of the Top 100 U.S. racehorses of the 20th Century and was inducted into the National Museum of Racing and Hall of Fame in 2001.

Holy Bull was a gray stallion who was bred in Florida by Rachel Carpenter's Pelican Stables. When Carpenter died in 1993, she bequeathed her horses to her long-time trainer Warren A. Croll, Jr. Croll was previously best known as the trainer of the brilliant sprinter Mr. Prospector.

Holy Bull was sired by Great Above, whose dam was the U.S. Racing Hall of Fame filly Ta Wee. Unlike most modern sire lines, Great Above did not descend from either Nearco or Native Dancer but instead from the now rare line of Plaudit, the Kentucky Derby winner of 1898.

Holy Bull, nicknamed "The Bull", stood 16.1 hands (65 inches, 165 cm) high. He was known for his brilliant speed and was able to win from the front or off the pace. Daily Racing Form caricaturist Peb captured his somewhat split personality by portraying him as a raging bull with a halo above his head. On the one hand, Holy Bull was aggressive on the track and inclined to bite. On the other, he loved people, leading Croll to call him a ham. "Whenever he sees a photographer," said Croll, "he'll stop and pose. He's getting smarter by the day."

Holy Bull was unbeaten in his four races as a two-year-old, including the Grade I Belmont Futurity. He made his racing debut on August 14, 1993 in a maiden special weight race at Monmouth Park, displaying "super speed" despite racing greenly. In his next start on September 2 in an allowance race at Belmont Park, he led from start to finish, winning by seven lengths.

On September 18, he made his stakes debut in the Belmont Futurity, where he faced the previously undefeated Dehere, the eventual champion two-year-old colt of 1993. Over a muddy track, Holy Bull went to the early lead with Dehere tracking the pace in third place. As they entered the stretch, Dehere moved into second and started to close ground on Holy Bull but could not get past. Holy Bull hung on to win by half a length in a time of 1:23.31 for seven furlongs.