Holy Cross Airport (IATA: HCR, ICAO: PAHC, FAA LID: HCA, formerly 4Z4) is a state-owned public-use airport located one mile (1.6 km) south of the central business district of Holy Cross, a city in the Yukon-Koyukuk Census Area of the U.S. state of Alaska.

Although most U.S. airports use the same three-letter location identifier for the FAA and IATA, Holy Cross Airport is assigned HCA by the FAA and HCR by the IATA.

Holy Cross Airport has one runway (1/19) with a gravel and dirt surface measuring 4,000 x 100 ft. (1,219 x 30 m).