House of Gucci is a 2021 American biographical crime drama film directed by Ridley Scott, based on the 2001 book The House of Gucci: A Sensational Story of Murder, Madness, Glamour, and Greed by Sara Gay Forden. The film follows Patrizia Reggiani (Lady Gaga) and Maurizio Gucci (Adam Driver) as their romance transforms into a fight for control of the Italian fashion brand Gucci. Jared Leto, Jeremy Irons, Jack Huston, Salma Hayek and Al Pacino also star.

Scott wanted to make a film about the Gucci dynasty after acquiring rights to Forden's book in the early 2000s. The project languished for several years, with several directors and actors rumored to be considered before Scott and Gaga became officially attached in November 2019. Much of the remaining cast joined the following summer, and filming began in Italy, lasting from February through May 2021.

The world premiere of House of Gucci was held at the Odeon Luxe Leicester Square in London on November 9, 2021. It was theatrically released in the United States on November 24, 2021. The film received mixed reviews from critics, who praised the cast's performances but criticized the inconsistent tone and editing. Gaga and Leto were nominated for the Screen Actors Guild Award, Critics' Choice Award, and Satellite Award for Best Actress and Best Supporting Actor, respectively, while Gaga also received nominations for the Golden Globe Award and BAFTA Award. The film also earned a nomination at the 94th Academy Awards for Best Makeup and Hairstyling. It grossed more than $153 million against a $75 million budget.

In Italy in 1978, Patrizia Reggiani is the office manager of her father's small trucking firm. At a party, she meets Maurizio Gucci, a law student and heir to a 50% interest in the Gucci fashion house through his father Rodolfo. Patrizia aggressively pursues the awkward Maurizio, charming him into a romantic relationship.

Rodolfo warns Maurizio that Patrizia is after only his wealth, and tells him that he will disinherit him if he marries Patrizia. Maurizio chooses Patrizia over his connection to Gucci, leaving the family. Patrizia and Maurizio marry, and he is hired by the trucking company.

When Patrizia becomes pregnant, she considers her child to be an avenue for familial reconciliation, and lets that information slip to Maurizio's uncle Aldo, who is delighted and takes the couple under his wing.

Aldo introduces Patrizia to his eccentric son Paolo, who aspires to be a designer within Gucci despite his apparent lack of talent. Aldo helps Maurizio and a terminally ill Rodolfo reconcile shortly before the latter's death. Rodolfo returns Maurizio to his will, but, before he dies, fails to sign the document bequeathing to him the 50% interest in Gucci shares, so Patrizia forges Rodolfo's signature on Rodolfo's updated testament.

Patrizia devises a plot to obtain a controlling interest in Gucci by acquiring some of Aldo's and Paolo's shares (the other 50%). She clashes with Aldo over the firm's clandestine sale of cheap "fake" Gucci products on the black market, and consults Giuseppina "Pina", a psychic, for guidance on how to manipulate Maurizio, who has little interest in Gucci, into taking a more active role within the company.