Indole-2-monooxygenase
Indole-2-monooxygenase
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Indole-2-monooxygenase

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Indole-2-monooxygenase

Indole-2-monooxygenase (EC 1.14.14.153, BX2 (gene), CYP71C4 (gene)) is an enzyme with systematic name indole,NAD(P)H:oxygen oxidoreductase (2-hydroxylating). It catalyses the following chemical reaction:


Indole-2-monooxygenase is a cytochrome P450 protein containing heme, isolated from Poaceae (grasses). It uses molecular oxygen for the oxidation and requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate. It is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.

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