Jon Lloyd Stryker (born c. 1958) is an American architect, philanthropist, and billionaire heir to the Stryker Corporation medical technology company fortune. Stryker is the founder and president of the Arcus Foundation, which primarily supports great ape conservation efforts and LGBT social justice, and has awarded over $500 million in grants. The threatened colobine species Rhinopithecus strykeri is named after him. According to Forbes, Stryker's net worth is estimated at $5.3 billion.

Stryker was born in Kalamazoo, Michigan. He is the youngest grandchild of Homer Hartman Stryker, founder of the medical supply company Stryker Corporation. Jon's father, Lee Stryker, died in an airplane crash in 1976.

Stryker earned a Bachelor of Arts degree in biology from Kalamazoo College in 1982. He now serves on the college's Board of Trustees and was the recipient of the college's 2010 Distinguished Service Award.

He also received a Master of Architecture degree from the University of California, Berkeley.

Stryker is a registered architect in Michigan and is president of Depot Landmark LLC, a development company specializing in the rehabilitation of historic buildings.

Stryker is a founding board member of Greenleaf Trust, a privately owned bank in Kalamazoo, Michigan.

Stryker is the founder and president of the Arcus Foundation, a private international philanthropic organization primarily supporting great ape conservation efforts and LGBT causes, as well as other social justice endeavors.

In 2024, Stryker was elected to the American Academy of Arts & Sciences.