Jones County is in the southeastern portion of the U.S. state of Mississippi. As of the 2020 census, the population was 67,246. Its county seats are Laurel and Ellisville.

Jones County is part of the Laurel micropolitan area.

Less than a decade after Mississippi became the country's 20th state, settlers organized this area of 700 sq mi (1,800 km²) of pine forests and swamps for a new county in 1826. They named it Jones County after John Paul Jones, the early American Naval hero who rose from humble Scottish origin to military success during the American Revolution.

Ellisville, the county seat, was named for Powhatan Ellis, a member of the Mississippi Legislature who claimed to be a direct descendant of Pocahontas. During the economic hard times in the 1830s and 1840s, there was an exodus of population from Southeast Mississippi, both to western Mississippi and Louisiana in regions opened to white settlement after Indian Removal, and to Texas. The slogan "GTT" ("Gone to Texas") became widely used.^{[citation needed]}

Jones County was in an area of mostly yeomen farmers and lumbermen, as the pine forests, swamp and soil were not easily cultivated for cotton. In 1860, the majority of white residents were not slaveholders. Slaves made up only 12% of the total population in Jones County in 1860, the smallest percentage of any county in the state.

Soon after the election of Abraham Lincoln as United States president in November 1860, slave-owning planters led Mississippi to join South Carolina and secede from the Union. These were the two states with the largest holdings of slaves. On November 29, 1860, the Mississippi state legislature called for a "Convention of the people of Mississippi" to be held to "adopt such measures for vindicating the sovereignty of the State as shall appear to them to be demanded." The Convention convened on January 7, 1861, and the elected representatives from the various counties of Mississippi voted 83–15 to secede from the Union. Notably, included in the vote to secede was the representative from Jones County, Mr. John H. Powell. Other Southern states would follow suit. As Mississippi debated the secession question, the inhabitants of Jones County voted overwhelmingly for the anti-secessionist John Hathorne Powell, Jr. In comparison to the pro-secessionist J.M. Bayliss, who received 24 votes, Powell received 374. But, at the Secession Convention, Powell voted for secession. Legend has it that, for his vote, he was burned in effigy in Ellisville, the county seat.

The reality is more complicated. The only choices possible at the Secession Convention were voting for immediate secession on the one hand, or for a more cautious, co-operative approach to secession among several Southern states on the other. Powell almost certainly voted for the more conservative approach to secession—the only position available to him that was consistent with the anti-secessionist views of his constituency.

Mississippi's Declaration of Secession reflected planters' interests in its first sentence: "Our position is thoroughly identified with the institution of slavery…" Jones County had mostly yeoman farmers and cattle herders, who were not slaveholders and had little use for a war over slavery.^{[citation needed]}