Jupiter Ascending is a 2015 space opera film written, directed and co-produced by the Wachowskis. Starring Channing Tatum and Mila Kunis with Sean Bean, Eddie Redmayne and Douglas Booth in supporting roles, the film centers on Jupiter Jones (Kunis), an ordinary cleaning woman, and Caine Wise (Tatum), an interplanetary warrior who informs Jones that her destiny extends beyond Earth. Supporting cast member Douglas Booth has described the film's fictional universe as a cross between The Matrix and Star Wars, while Kunis identified indulgence and consumerism as its underlying themes.

The film was produced by Grant Hill and the Wachowskis, making Jupiter Ascending Hill's seventh collaboration with the Wachowskis as producer or executive producer. Several more longstanding Wachowski collaborators since the creation of the Matrix films contributed to the picture, including production designer Hugh Bateup, visual effects supervisor Dan Glass, visual effects designer John Gaeta, standby propman Alex Boswell, sound designer and supervising sound editor Dane A. Davis and costume designer Kym Barrett. Other notable past collaborators include Speed Racer music composer Michael Giacchino, Cloud Atlas director of photography John Toll along with its editor Alexander Berner and hair and make-up designer Jeremy Woodhead, who worked on both.

Jupiter Ascending was released in the United States on February 6, 2015, by Warner Bros. Pictures. It received negative reviews from critics; despite praise for the visual effects, the narrative was criticized as confusing. It grossed $184 million against a $176–210 million budget during its theatrical release.

Earth and countless other planets were established by families of transhuman and alien royalty to harvest the resulting organisms to produce a perpetual life-extending youth serum for the elites on other planets. After the matriarch of the House of Abrasax, the most powerful of the alien dynasties, dies, her children — Balem, Kalique, and Titus — quarrel over the inheritance. Balem inherits control of the Abrasax business empire, while Kalique inherits the planet Cerise and Titus spends his inheritance on a lavish spaceship. None of them are named Sovereign of Abrasax. Instead, they are styled First, Second and Third Primary.

After Maximilian Jones is killed in a robbery, his wife Aleksa (née Bolotnikov), whom he met in Saint Petersburg, Russia, names their daughter Jupiter after his favorite planet, and they relocate to Chicago to live with her family. Years later, Jupiter makes a modest living as a housekeeper to her wealthy neighbors. Desiring a telescope, she agrees to sell her egg cells and uses her friend Katharine Dunlevy's name as a pseudonym. At Katharine's house, extraterrestrial "Keepers" attack the women. Jupiter photographs them, but they erase both women's memories of the incident immediately afterwards. She later notices the strange photograph on her phone while waiting at an egg donation clinic, but cannot recall anything about it. During the procedure, the doctors and nurses are revealed as Keepers sent to kill her, but Caine Wise, a former soldier dispatched by Titus to bring her to him, rescues her. As Caine and Jupiter flee, a squad of Keepers destroys their spaceship, but he fends off the attack and kills them before hijacking one of their vehicles, realizing that Jupiter must be highly significant to Titus and Balem, who are revealed to have dispatched the Keepers to Earth.

Caine takes Jupiter to the hideout of Stinger Apini, another former soldier living in exile on Earth. After learning she can control the bees in Stinger's residence, Jupiter discovers that she is galactic royalty. Stinger agrees to help Jupiter, but she is captured by Balem's hunters and bribed by Kalique to bring Jupiter to her alcazar on Cerise. There, Kalique explains that Jupiter is genetically identical to the House of Abrasax's long-dead matriarch, and therefore she is the Earth's rightful owner.

Supported by Captain Diomika Tsing of the intergalactic police force, Aegis, Caine retrieves Jupiter from Kalique and takes her to the capital planet, Orous, to claim her inheritance as Sovereign of Abrasax. Once claimed, Jupiter would gain control of Abrasax Industries and displace Balem as titleholder of Earth. In another attempt to lure Jupiter to him, Balem sends Greeghan to kidnap her family. On the way back to Earth, Titus's henchmen capture Jupiter and detain Caine as punishment for not bringing her to him. Titus reveals to Caine his plan to marry Jupiter, kill her, and claim Earth. Titus then throws Caine into the void of space and attempts to seduce Jupiter, declaring his intention to dismantle the youth serum trade, of which Earth is the next intended source. Caine survives being spaced and returns with Stinger to save Jupiter at the altar before she is married. Jupiter asks to return home but learns that her family has been taken hostage by Balem.

At his refinery inside the Great Red Spot, Balem demands Earth in exchange for Jupiter's family. Realizing that Balem cannot "harvest" Earth without her permission, Jupiter refuses. Caine infiltrates the refinery and damages its gravity hull, causing the refinery to begin collapsing. While the occupants evacuate the refinery, Tsing's ship moves in and rescues Jupiter's family. Jupiter survives the collapsing structures, only to land at the feet of Balem, who tries to kill her; she fights him off before Balem falls to his death. Caine saves her as the refinery is in its final stages of collapse. Tsing opens a portal to Earth and prepares to evacuate, potentially leaving Caine and Jupiter behind. However, she is relieved that they have survived and crossed the portal, along with Tsing's ship. Jupiter's family returns home with no memory of their disappearance, while Jupiter secretly retains ownership of the Earth. Caine's rank in the Legion is restored, and he and Jupiter begin a relationship.