Lee Dong-wook (Korean: 이동욱; born 6 November 1981) is a South Korean actor and presenter. He is best known for his leading roles in the television dramas My Girl (2005–2006), Scent of a Woman (2011), Guardian: The Lonely and Great God (2016–2017), Life (2018), Hell Is Other People (2019), Tale of the Nine Tailed (2020), Bad and Crazy (2021), Tale of the Nine Tailed 1938 (2023), and A Shop for Killers (2024). He is also the host of the talk show Strong Heart (2012–2013), boy group survival reality show Produce X 101 (2019), and his own American-style talk show Wook Talk (2019).

In 2005, Lee enrolled in Joongbu University, majoring in media and broadcasting arts.

Lee made his acting debut in 1999 in an MBC single-episode drama after winning the grand prize in the V-NESS model contest of the same year. The PD of the drama saw Lee, and proceeded to cast him in the teen drama School 2. Lee started to gain recognition with his performance in School 3.

Lee hit stardom with 2005 romantic comedy My Girl. The drama series became a hit during its run both domestically and across Asia, and made Lee a Korean Wave star.

He has since starred in noir Bitter Sweet Life (2008), courtroom dramedy Partner (2009), melodrama Scent of a Woman (2011), baseball rom-com Wild Romance (2012), period thriller The Fugitive of Joseon (2013), and revenge drama Hotel King (2014), in which he reunited with My Girl co-star Lee Da-hae. He then starred in fantasy-action series Blade Man (2014) and romance drama Bubble Gum (2015).

Lee and comedian Shin Dong-yup took over as MCs of talk show Strong Heart from April 2012 to January 2013. Lee also joined the reality show Roommate, which aired from 2014 to 2015.

From 2016 to 2017, Lee starred alongside Gong Yoo in Kim Eun-sook's fantasy-romance drama Guardian: The Lonely and Great God playing a grim reaper. The drama was a hit, and along with its success, helped in the resurgence of Lee's acting career.

In 2018, Lee starred in the medical drama Life as a doctor who works at the ER Department.