The following is a list of people who have served as mayor of the city of Houston in the U.S. state of Texas.

To file to run for mayor, a person must be a qualified voter of the city of Houston, and have has resided in the city for at least 12 months immediately preceding the election day; to serve, the person must continue to be a qualified voter and resident. Elections for mayor are held every other odd-numbered year. To serve as mayor of Houston, a person must be a qualified voter and resident of the City. To win the election, a candidate is required to receive the majority of votes; if no candidate receives a majority, a run-off election between the top two

Until 2015, the term of the mayor was two years. Beginning with the tenure of Bob Lanier, the city charter imposed term limits on officeholders of no more than three terms (six years total). On November 3, 2015, voters approved Proposition 2, which extended the terms of the Mayor, City Controller and City Councilmembers to four years, while imposing a limit of two terms.