Lucifer is the name of two unrelated characters appearing in American comic books published by Marvel Comics. One is an alien supervillain of the X-Men and the other is a villain of Ghost Rider and is referred to as the Prince of Darkness.

The first Lucifer first appearance was in The X-Men #9 (Jan. 1965) and was created by Stan Lee and Jack Kirby. He is an agent of the Quists, an alien race who are also known as the Arcane.

The alien being known as Lucifer was born on the planet Quistalium, in the Quistraa star system in the Milky Way Galaxy, who had invaded many worlds. He first comes to Earth as an advance agent for the invasion of Earth by the Arcane (also known as the Quists), and places several humans under his hypnotic control, allowing him to take control of a small area. This invasion is foiled by a young Charles Xavier (later Professor X, leader of the X-Men). In retaliation, Lucifer drops an enormous stone block on Xavier, leaving him paraplegic.

Lucifer returns to Earth years after paralyzing Xavier and battles Xavier once again in the Balkan Mountains. He has a device attached to his own heart that will set off a bomb if he is killed, but it is defused by Cyclops. Lucifer later manipulates the Blob and Unus into framing the X-Men as criminals. He is thwarted by the X-Men and teleported from Earth by the Quistalian Supreme for punishment.

Lucifer is exiled to an alternate realm known as the "Nameless Dimension". There, he uses "ionic energy" to give himself superhuman strength and the ability to project force beams from his hands, in addition to his apparently pre-existing telepathic powers. He continued to try conquering Earth by using his "dimensional transmitter" to imbue humans with ionic energy and turning them into his minions. After several failed attempts, Lucifer's masters "terminate" him for his failures and replace him with the computer Dominus.

Lucifer is a supervillain in Marvel Comics, mostly associated with Ghost Rider.

Lucifer is a powerful entity whose true history is unknown. It is believed that he was once an angel who led other angels in banishing the N'Garai from Earth and led a group of followers in a rebellion against God. Following his defeat, Lucifer and his lieutenants were cast down to Hell as punishment, where they transformed into demons over time.

Lucifer believes that, if he extinguished Ghost Rider's human soul, he could be made into a soulless killing machine who he could use to extinguish all humanity. For years, Lucifer with the aid of the other Hell-lords had made many attempts on Ghost Rider's soul, but all have failed.